Research

Eustachian Tube Development Study

Eustachian Tube Growth and Development: Anatomy/Function

Protocol Description

This study will measure Eustachian tube function and facial growth over time in groups of children with the two types of otitis media and with little past otitis media. These measures will be used to determine if facial growth is related to improved Eustachian tube function and to the resolution of otitis media. Additionally, findings will be used to see if the better function explains why young children “outgrow” otitis media as they get older, and to determine if these measures are different for the children in the three groups.

Eligibility Criteria

Children of both genders will be entered into the study at age 3 and assigned to one of the following groups: 1) those with many ear infections (recurrent acute otitis media), 2) those who have had long-term fluid in the ears without symptoms of infection (otitis media with effusion) and 3) children who have had very little middle-ear disease (control).
Boys: 3 years old
Girls: 3 years old

Requirements
Children enrolled in the study will have examinations done on a 6-month schedule until they are 7 years old. During examinations, a variety of tests will be performed to measure Eustachian tube function, and facial measurements will be recorded. At specific intervals, other specialized tests, such as cephalometric x-rays and magnetic resonance imaging, will be done.
Visits: 8
Duration: 4 years

Status: Open for Enrollment

Source of Support
National Institute on Deafness and Other Communication Disorders
National Institutes of Health

Additional Resources
Study description at National Institutes of Health