Research

Eustachian Tube Function During Cold or Flu

Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 2

Protocol Description

This study explores the role that the Eustachian tube function plays in causing middle-ear disease during cold or flu episodes. The goal is to determine if the decreased ability of the Eustachian tube to open during a cold or flu leads to middle-ear disease.

Eligibility Criteria

The child portion of this study is presently closed to enrollment, but includes children ages 2-6 years of both genders, who were already enrolled in the study “Role of Virus and Genetic Susceptibility in Otitis Media.” For the adult portion of the study, male and female volunteers ages 18 to 54, who are participating in “Social and Psychological Risks for Infectious Disease,” are eligible.
Males: ages 18 to 54 years
Females: ages 18 to 54 years

Requirements
Participants in the study will be given Eustachian tube function tests, including measurements by tympanometry and sonotubometry at the Ear Nose and Throat Research Center at Children’s Hospital of Pittsburgh of UPMC and, for adult participants some additional testing will be required.
Visits: Done in conjunction with protocols noted under Eligibility Criteria
Duration: Not applicable

Status: Closed to Enrollment

Source of Support
National Institute on Deafness and Other Communication Disorders
National Institutes of Health

Additional Resources
Study Description at National Institutes of Health