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412-692-9351 Phone
412-692-7636 Fax

John F. Alcorn, PhD

Job Title Research Assistant Professor, Department of Pediatrics, Children’s Hospital of Pittsburgh of UPMC
One Children's Hospital Drive
4401 Penn Ave., Suite Rangos Research Building, 9th Floor
Pittsburgh, PA 15224
412-692-9351 Phone
412-692-7636 Fax

Education and Training

Graduate School:

1998 MSc, Youngstown State University, Youngstown, OH
2003 PhD, Duke University Medical Center, Durham, NC
 

Post Graudate School:

2005 Post-Doctoral Associate, Department of Pathology, University of Vermont
2007 Post-Doctoral Fellow, National Research Service Award, Department of Pathology, University of Vermont

Memberships

  • American Thoracic Society

Publications

  • Nagata T, McKinley L, Peschon JJ, Alcorn JF, Aujla SJ, and JK Kolls. Requirement of IL-17RA in Con A Induced Hepatitis and Negative Regulation of Il-17 Production in Mouse T Cells. J Immunol 181 : 7473-79, 2008.
  • McKinley L, Alcorn JF, Peterson A, Kapadia S, Logar A, Henry A, Irvin CG, Piganelli J, Ray A, and JK Kolls. TH17 Cells Mediate Steroid-Resistant Airways Inflammation and Airways Hyperresponsiveness in mice. J Immunol, 181(6) : 4089-97, 2008.
  • Alcorn JF, van der Velden J, Brown AL, McElhinney B, Irvin CG, and YMW Janssen-Heininger. c-Jun N-terminal Kinase 1 is required for the development of pulmonary fibrosis. Am J Respir Cell Mol Biol, In Press, 2008.

    View Dr. Alcorn's full list of publications from PubMed.

Research Interests

  • Lung Infection
  • Pulmonary Immunity
  • Th17 cells and IL-17
  • c-Jun N-terminal Kinase Signaling
  • Asthma
  • Transforming Growth Factor – beta and Fibrosis

Active Research Projects / Grants

  • Use of neutralizing antibodies against IL-17A, IL-17F, and IL-23 in murine models of pulmonary inflammation and airway hyperresponsiveness
  • Mechanisms of TH17 Mediated Allergic Airway Disease
Last Update
October 10, 2011
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Last Update
October 10, 2011
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