Research
Genetic Relationships Between Parents and Transplant Recipients
Transmissible Genetic Traits in Transplant Outcomes
Protocol Description
This study is examining whether transplant outcomes are influenced by certain changes in transplant recipients’ genes. Genes contain the information necessary to control activities of a cell, including the accurate production of proteins, which are necessary for all types of cell function. By measuring the structure of genes within the cells of a parent or sibling of a transplant recipient, and comparing it with the structure of genes within the recipient, researchers hope to be able to detect changes that will help them understand why different people with organ transplants have different outcomes after transplantation. This information may also help in tailoring the best anti-rejection treatment for each person.
Eligibility Criteria
Parents or siblings of patients who have received a transplant of the liver, intestine, kidney, pancreas, heart or lung, alone or in combination, are eligible for participation in the study.
Males: Ages 18 and older
Females: Ages 18 and older
Requirements
A small blood and/or saliva sample will be collected at the time consent is provided for participation in the study.
Visits: 1
Duration: Not applicable
Status: Open for Enrollment
Source of Support
Pediatric Transplantation Department, Children’s Hospital of Pittsburgh of UPMC
Primary Investigator(s)
Rakesh Sindhi, MD
Contact Information
To get started, please contact:
Sara Snyder, BS
412-692-5297
