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Fernando Holguin, MD, MPH

Job Title Medical Director, Pediatric Environmental Medicine Center, University of Pittsburgh, Children’s Hospital of Pittsburgh of UPMC
Job Title Assistant Professor of Medicine, University of Pittsburgh
Job Title Associate Researcher, National Institute of Public Health, Mexico
4401 Penn Avenue, Suite Floor 3
Pittsburgh, PA 15224
412-692-5630 Phone
412-692-6645 Fax

Education and Training

Medical School:

1991 MD, La Salle University School of Medicine, Mexico City, Mexico
2006 MPH, Rollins School of Public Health, Emory University, Atlanta, GA


1996 Internal Medicine, Emory University School of Medicine, Atlanta, GA


1999 Pulmonary and Critical Care Medicine, Emory University School of Medicine, Atlanta, GA


  • American Thoracic Society
  • Southern Society of Clinical Investigation
  • European Respiratory Society

Board Certifications

  • Pulmonary Medicine 
  • Critical Care Medicine


  • Award of excellence for establishing the Asthma Translational Research Program within the Emory Respiratory Health Center
  • Fellow’s Faculty Teaching Award, Pulmonary, Allergy and Critical Care, Emory University
  • Emory University Dean’s Faculty Teaching Award
  • National EPA Children’s Environmental Excellence Award  
  • 2004, 2006 Golden Apple Award (Outstanding Teacher in Medicine), Emory University  
  • Awarded Best Resident in Internal Medicine, Emory University
  • Inducted into Alpha Omega Alpha
  • Elected, Southern Society of Clinical Investigation


  • Taylor B, Mannino D, Brown C, Crocker D, Twum-Baah N, Holguin F. Body mass index and asthma severity in the National Asthma Survey. Thorax 2008, 63(1):14-20.
  • Stephen J. Onufrak, PhD, Jerome L. Abramson, PhD, Harland D. Austin, DSc, Fernando Holguin, MD, MPH, William M. McClellan, MD, MPH, and L. Viola Vaccarino, MD, PhD. Relation of Adult-Onset Asthma to Coronary Heart Disease and Stroke. American Journal of Cardiology 2008;101:1247–1252.
  • Alexandra Schneider, Lucas Neas, Margaret C. Herbst,Martin Case, Ronald W. Williams, Wayne Cascio, Alan Hinderliter, Fernando Holguin, John B. Buse, Kathleen Dungan, Myna Styner, Annette Peters, and Robert B. DevlinEndothelial Dysfunction: Associations with Exposure to Ambient Fine Particles in Diabetic Individuals. Environmental Health Perspectives, doi:10.1289/ehp.11666. Online 31 July 2008.

    View Dr. Holguin's full list of publications from PubMed.

Research Interests

  • Effects of air pollution on cardiovascular disease
  • Defining the mechanisms by which obesity leads to an increase risk for asthma
  • Understanding disparities in pulmonary health outcomes at a national level

Active Research Projects / Grants

  • A randomized, placebo-controlled study of pioglitazone to treat poorly controlled obese asthmatics
  • Effect of a dietary weight loss intervention on airway oxidative stress, asthma control and lung function in a cohort of asthmatic children in Mexico City 
  • Airway adipokines and alveolar macrophage PPARγ expression. A link between obesity and airway oxidative stress in asthma
  • A randomized pilot study to evaluate the effects of pioglitazone and standard therapy vs placebo and standard therapy to treat obese, uncontrolled asthmatics
  • Effects of weight loss on airway inflammation and oxidation in asthmatic subjects undergoing bariatric surgery
  • Virtual reality skills training: nicotine dependence
  • The role of leukotrienes in the asthma obesity phenotype
  • Effects of air pollution on the respiratory health of children with Sickle Cell Disease in Atlanta
  • The role of chronic alcohol consumption in airway oxidative stress in patients with and without asthma
  • A bi-national study of asthma and air pollution in children in the US-Mexico border
Last Update
April 5, 2010
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Last Update
April 5, 2010