Research

Intestinal Failure in Children: A Contemporary Retrospective Review

Protocol Description

The objective of this multi-center review is to determine possible demographic, clinical and nutritional risk factors that predict certain critical outcomes related to intestinal failure. These include the need for long-term parenteral nutrition (nutrition provided intravenously); discontinuation of parenteral nutrition; development of cholestasis; and the need for intestinal transplant. This investigation will collect, maintain, analyze and report the clinical, nutritional, surgical and epidemiological data in children with intestinal failure, with a longer-term objective of providing a foundation for future studies involving controlled therapeutic trials.

Eligibility Criteria

With permission, the retrorespective review will look at medical records of patients of less than 12 months of age who received parenteral nutrition for at least 60 days as a consequence of intestinal failure or short bowel syndrome between Jan. 1, 2000 and Dec. 31, 2004.
Boys: Birth to 12 months
Girls: Birth to 12 months

Requirements
Participation is limited to placement of the patients’ identifiable medical information related to intestinal disease, as well as parenteral therapy status, into the data collection for this review.
Visits: Not Applicable
Duration: Not Applicable

Status: Open for Enrollment

Source of Support
National Institutes of Health