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412-692-6110 Phone
412-692-6116 Fax

George V. Mazariegos, MD, FACS

George V. Mazariegos, MS, FACS, chief, Pediatric Transplantation
Job Title Chief, Pediatric Transplantation
Job Title Professor of Surgery and Critical Care, University of Pittsburgh School of Medicine
Job Title Faculty, McGowan Institute for Regenerative Medicine
4401 Penn Avenue
Pittsburgh, PA 15224
412-692-6110 Phone
412-692-6116 Fax

Education and Training

Medical School:

1986 Northwestern University Medical School, Chicago


1990 Michigan State University, Butterworth Hospital, Grand Rapids, Mi.
1991 Chief Resident, Michigan State University, Butterworth Hospital, Grand Rapids, Mi.


1992 University of Pittsburgh Medical Center, Critical Care Medicine Fellowship
1993 University of Pittsburgh Medical Center, Hepatic and Multivisceral Transplantation Fellowship


  • Society of University Surgeons
  • International Pediatric Transplant Association
  • American Society of Transplant Surgeons


  • 1999 Service Star Award, Children's Hospital of Pittsburgh
  • 1992 Critical Care Fellow of the Year, University of Pittsburgh Multidisciplinary Critical Care Training Program


  • Mazariegos GV, Morton DH, Sindhi R, Soltys K, Nayyar N, Bond G, Shellmer D, Shneider B, Vockley J, Strauss KA. Liver Transplantation for Classical Maple Syrup Urine Disease: Long-Term Follow-Up in 37 Patients and Comparative United Network for Organ Sharing Experience. J Pediatr. 2011 Aug 10.
  • Nayyar NS, McGhee W, Martin D, Sindhi R, Soltys K, Bond G, Mazariegos GV. Intestinal transplantation in children: a review of immunotherapy regimens. Paediatr Drugs. 2011 Jun 1;13(3):149-59.
  • Papachristou GI, Abu-Elmagd KM, Bond G, Costa G, Mazariegos GV, Sanders MK, Slivka A. Pancreaticobiliary complications after composite visceral transplantation: incidence, risk, and management strategies. Gastrointest Endosc. 2011 Jun;73(6):1165-73. Epub 2011 Apr 8.

Biography Summary

George V. Mazariegos, MD, is the director of Pediatric Transplantation at Children's Hospital of Pittsburgh of UPMC. He also is director of Pediatric Transplantation at the Thomas E. Starzl Transplantation Institute and an associate professor at the University of Pittsburgh in the departments of Surgery, Anesthesiology, and Critical Care Medicine.

Dr. Mazariegos earned a bachelor's degree in medical science at Northwestern University in Evanston, Ill., in 1984. Two years later, he graduated from Northwestern University Medical School. He completed residency training at Michigan State University in Grand Rapids and completed his fellowship training at the University of Pittsburgh in 1993. He joined the Thomas E. Starzl Transplantation Institute in 1994 and Children's Hospital of Pittsburgh in 1997 as co-director of Pediatric Liver and Intestine Transplantation.

Dr. Mazariegos specializes in the treatment of pediatric patients who have liver and/or intestinal disease that require transplantation. He also cares for children who develop acute liver failure and who may require specialized liver support therapies until they recover or until donor organs are available.

Dr. Mazariegos' research focuses on further refining immunosuppression therapy to improve transplant outcomes and quality of life. He currently is leading clinical efforts to evaluate lowering or withdrawing immunosuppression in long-term liver transplant recipients in order to maximize quality of life and minimize post-transplant complications. Dr. Mazariegos also is analyzing immunologic characteristics of patients successfully withdrawn from immunosuppression. This study, sponsored by the Immune Tolerance Network, is attempting to develop a "tolerance assay" that can be used to prospectively characterize patients who may be candidates for less immunosuppression.

Dr. Mazariegos has authored or co-authored more than 70 original articles, more than 80 abstracts and 10 book chapters. He has been active in coordinating the development of bio-artificial liver support systems for use in patients with acute liver failure. He also serves on the Scientific Advisory Board of Studies in Pediatric Liver Transplantation, an international registry of pediatric liver transplantation.

Dr. Mazariegos' work has earned him memberships in numerous professional and scientific societies, including the Society of University Surgeons and the International Pediatric Transplant Association. He was named Critical Care Fellow of the Year in 1992 by the University of Pittsburgh Multidisciplinary Critical Care Training Program, and in 1999 he received Children's Hospital's Service Star Award.

Last Update
April 16, 2013
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Last Update
April 16, 2013