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412-692-5055 Phone
412-692-7693 Fax

Linda M. McAllister-Lucas, MD, PhD

Linda McAllister-Lucas, MD, PhD
Job Title Chief of Service, Hematology/Oncology
Job Title Associate Professor of Pediatrics, University of Pittsburgh School of Medicine
4401 Penn Avenue, Suite Floor 9
Pittsburgh, PA 15224
412-692-5055 Phone
412-692-7693 Fax

Education and Training

Medical School:

1996 MD, Vanderbilt University School of Medicine, Nashville, Tenn.
1994 PhD, Vanderbilt University School of Medicine, Medical Scientist Training Program (MSTP), Nashville, Tenn.


1999 Pediatrics, University of Michigan, Department of Pediatrics, Ann Arbor, Mich.


2002 Research Fellow, Cancer Biology, University of Michigan, Department of Pathology, Ann Arbor, Mich.
2002 Pediatric Hematology/Oncology, University of Michigan, Department of Pediatrics, Ann Arbor, Mich.



  • Midwest Society for Pediatric Research (MWSPR)
  • American Association for Cancer Research (AACR)
  • Society for Pediatric Research (SPR)
  • American Society of Pediatric Hematology and Oncology
  • American Society of Hematology (ASH)

Board Certifications

  • American Board of Pediatrics, Diplomate
  • Pediatric Hematology and Oncology


  • 2012 Inaugural Laurence Boxer Honorary Lectureship, University of Michigan
  • 2010 TAMS Teaching Award, University of Michigan Medical School
  • 2008 America’s Top Doctors     
  • 2007 Elizabeth Caroline Crosby Award for the Advancement of Women In Science and Engineering
  • 2007 Best Doctors in America
  • 2006 Society for Pediatric Research (SPR) Young Investigator
  • 2006 Laura and Greg Norman Research Fellow, National Childhood Cancer Foundation
  • 2005 Faculty Award for Basic Science Research, Department of Pediatrics, University of Michigan
  • 2005 Pediatric Academic Societies Young Investigator Travel Award
  • 2002 Doris Duke Clinical Scientist Development Award
  • 1999 Outstanding Resident Teaching Award, Department of Pediatrics, University of Michigan
  • 1993 Clarence Darrow Award for Most Outstanding Lecturer in Physiology, Vanderbilt University School of Medicine
  • 1987 School of Life Sciences Fellowship, University of Illinois
  • 1987 Lawrence McKinley Gould Award, Carleton College
  • 1983 William Carleton Scholar, Carleton College


  • Bailey KM, Castle VP, Hummel JM, Piert M, Moyer J, and McAllister-Lucas LM (2012) Thalidomide Therapy for Aggressive Histiocytic Lesions in the Pediatric Population.  J. Pediatr. Hematol. Oncol., 34:480-3.
  • Van Beek M, Oravecz-Wilson KI, Delekta PC, Gu S, Li X, Jin X, Apel IJ, Konkle KS, Feng Y, Teitelbaum DH, Ruland J, McAllister-Lucas* LM, and Lucas* PC (2012) Bcl10 links saturated fat overnutrition with hepatocellular NF-B activation and insulin resistance.  Cell Reports, 1:444-452.
  • Shukla N, Kobos R, Renaud T, Feldstein J, McAllister-Lucas LM, and Steinherz P (2012) Successful treatment of refractory metastatic histiocytic sarcoma with alemtuzumab. Cancer, 118:3719-24.
  • McAllister-Lucas LM, Baens M, Lucas PC. MALT1 protease: a new therapeutic target in B lymphoma and beyond? Clin Cancer Res. 2011 Nov 1;17(21):6623-31.
  • Rosebeck S, Madden L, Jin X, Gu S, Apel IJ, Appert A, Hamoudi RA, Noels H, Sagaert X, Van Loo P, Baens M, Du MQ, Lucas PC, McAllister-Lucas LM. Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. Science. 2011 Jan 28;331(6016):468-72.

Research Interests

  • Molecular pathogenesis of Non-Hodgkin Lymphoma
  • Molecular mechanisms by which inflammation promotes tumor development and metastasis

Active Research Projects / Grants

  • GPCR Signaling Through a Novel NF-B Pathway
  • A Novel Signaling Pathway Mediating Hypertension- and Obesity-Dependent Insulin Resistance
  • Angiotensin II Signaling Through a Novel NF-B Pathway
  • Multiple Roles of the API2 Moiety in API2-MALT1-Mediated Lymphomagenesis
Last Update
November 23, 2014
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Last Update
November 23, 2014