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Physician Profile

412-648-3291 Phone

412-624-6666 Fax

Job Title Associate Professor, Surgery and Immunology

4401 Penn Avenue, Suite Floor 3

Pittsburgh, PA 15224

412-648-3291 Phone

412-624-6666 Fax

Email metesdm@upmc.edu

Medical School:	1985 Faculty of General Medicine, Institute of Medicine and Pharmacy, Bucharest, Romania
Residency:	1991 Hematology, Institute of Hematology, Bucharest, Romania
Fellowship:	1996 Immunology/Molecular Biology, Department of Pathology, University of Pittsburgh Cancer Institute, Pittsburgh, Pa. 1994 Immunology, Department of Pathology, University of Pittsburgh Cancer Institute, Pittsburgh, Pa.

2009-2011 Roche Organ Transplantation Research Foundation Award
2009 Selected lecturer for the “Vice Chancellor Seminar”, UPSOM, Pittsburgh, Pa.
2003 Travel Award to the 3rd Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS) 2003 Paris, France
2001-2002 Junior Faculty Research Award, Lymphoma Research Foundation of America
2000 Young Investigator Award for the Transplant 2000 Meeting, American Society of Transplantation, Chicago, Ill.
1996, 1997 University of Pittsburgh Cancer Institute, Director’s Award for scientific excellence and potential 2nd place, UPCI Scientific Retreat, Johnstown, Pa.
1994-1995 Postdoctoral Fellowship, NCI, NIH
1992-1994 Postdoctoral Fellowship, Fogarty Foundation, NIH
1990 Romanian Society for Immunology: Award for Excellence in Immunology, 7th National Scientific Meeting, Cluj, Romania

Macedo C, Walters JT, Orkis EA, Elinoff BD, Fedorek SP, Chalasani G, Kumico , Demetris AJ, Zeevi A, Shapiro R, Lakkis FG, Metes D. Long-term effects of Alemtuzumab induction on regulatory and memory T cell subsets and their relationship to clinical outcome in kidney transplant recipients. Transplantation; 2012; 93(8):813-21.
Wiesmayr S., Webber SA., Smith L., Popescu I., Macedo C., Metes D. Decreased NKp46 and NKG2D expression in the presence of elevated PD-1 lead to significant NK cell functional alterations in pediatric Tx patients with PTLD. European Journal of Immunology; 2012; 42:541-550.
Macedo C, Webber SA, Donnenberg A, Popescu I, Hua Y, Green M, Rowe D, Smith L, Brooks M, Metes D. EBV-specific CD8+ T cells from asymptomatic pediatric thoracic transplant patients carrying chronic high EBV loads display contrasting features: activated phenotype and exhausted function. Journal of Immunology; 2011; 186(10):5854-62.