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Uma M. Nagarajan, PhD

Uma M. Nagarajan, PhD
Job Title Assistant Professor, Department of Pediatrics, The Division of Infectious Diseases, Children's Hospital of Pittsburgh of UPMC
One Children's Hospital Drive
4401 Penn Ave., Suite Floor 9
Pittsburgh, PA 15224
412-692-7438 Phone
412-692-7016 Fax

Education and Training

Graduate School:

1988 Biochemistry, University of Madras, Madras, India 

Post Graduate School:

1997 Biochemistry, Madurai-Kamaraj University, India
 

Memberships

  • American Association for the Advancement of Science (AAAS)
  • International Endotoxin and Innate Immunity society (IEIIS) 
  • American Association of Immunologist (AAI)
  • American Association of Microbiologist (ASM)

Awards

GENBANK Submissions

  • Acc. No. NM_134440.  Homo sapiens regulatory factor X-associated ankyrin-containing protein (RFXANK), transcript variant 2, mRNA. Nagarajan,U.M., Louis-Plence,P., DeSandro,A., Nilsen,R., Bushey,A and Boss,J.M.
  • Acc. No. NM_003721.  Homo sapiens regulatory factor X-associated ankyrin-containing protein (RFXANK), transcript variant 1, mRNA. Nagarajan,U.M., Louis-Plence,P., DeSandro,A., Nilsen,R., Bushey,A and Boss,J.M.
  • Acc. No. AY303775 . Cavia porcellus CD8 beta-2 mRNA, complete cds; alternatively spliced.  Nagarajan,U.M., O'Connell,C. and Rank,R.G.
  • Acc. No. AY303774.  Cavia porcellus CD8 beta mRNA, complete cds. Nagarajan,U.M., O'Connell,C. and Rank,R.G.
  • Acc. No. AY303773.   Cavia porcellus CD8 alpha mRNA, complete cds. Nagarajan,U.M., O'Connell,C. and Rank,R.G.

Publications

  • Nagarajan UM*, Sikes JD, Yeruva L, and Prantner D. Significant role of IL-1 signaling, but limited role of inflammasome activation in oviduct pathology during Chlamydia muridarum genital infection. Journal of Immunology 188(6):2866-75, 2012.
  • Pokrovskaya ID , Szwedo JW., Goodwin A., Lupashina TV., Nagarajan UM*., and Lupashin VV*.  Chlamydia trachomatis hijacks intra-Golgi COG complex-dependent vesicle trafficking pathway. (* equal contribution) Cellular Microbiology, 14:656-68, 2012.
  • Prantner D, Sikes, JD, Hennings L, Savenka AV, Basnakian AG, and Nagarajan UM*.  IRF3 protects from uterine horn pathology during Chlamydia muridarum genital infection in mice. Infection and Immunity 79: 3922-33, 2011.[PubMed]

Research Interests

  • Innate immune responses to genital chlamydial infection

Active Research Projects / Grants

  • Mechanism of Chlamydia-induced type I IFN response
  • Role of Golgi trafficking during Chlamydia trachomatis infection
Last Update
April 16, 2013
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Last Update
April 16, 2013
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