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Physician Profile
412-692-5641
Phone
412-692-6550
Fax
John A. Ozolek, MD
Job Title
Assistant Professor of Pathology, Children's Hospital of Pittsburgh of UPMC
4401 Penn Avenue, Suite Floor B
Pittsburgh,
PA
15224
412-692-5641
Phone
412-692-6550
Fax
Email
ozolekja@upmc.edu
Education and Training
|
Medical School: |
1989 University of Pittsburgh School of Medicine, Pittsburgh, PA |
|
Residency: |
1992 Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA |
|
Fellowship: |
1995 Magee Womens Hospital, Pittsburgh, PA |
Memberships
- United States and Canadian Academy of Pathology
- American Society for Cell Biology
- International Society for Stem Cell Research
Board Certifications
- Neonatal-Perinatal Medicine
- Anatomic Pathology
- Pediatric Pathology
Awards
- National Dean’s List
- Russell M. Lawall Prize in Biological Sciences (Awarded to graduating Case Institute of Technology student for outstanding undergraduate performance in biological sciences)
- Health Professions Scholarship Program (Scholarship recipient from the United States Air Force)
- Style and Grace Award (Awarded for exemplary professionalism at Keesler Medical Center)
- Air Force Achievement Medal
- Outstanding Junior Resident in Autopsy Pathology
- Outstanding Web Case Publication in Anatomic Pathology
- Chief Resident in Anatomic Pathology
- Best Poster Presentation in Otorhinolaryngology—Head and Neck Pathology at the 94th Annual Meeting of the United States and Canadian Academy of Pathology
Publications
- Ozolek JA, Hunt JL. Tumor suppressor gene alteration in respiratory epithelial adenomatoid hamartoma (REAH): Comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa. Am J Surg Pathol 2006;12:1576-1580.
- Ozolek JA, Jane EP, Krowsoski L, Sammak PJ. Human embryonic stem cells (HSF-6) show greater proliferation and apoptoses when grown on glioblastoma cells than mouse embryonic fibroblasts at day 19 in culture: Comparison of proliferation, survival, and neural differentiation on two different feeder cell types. Stem Cells and Development 2007;16:403-412.
- Ozolek JA, Barnes EL, Hunt JL. Basal/myoepithelial cells in chronic sinusitis, respiratory epithelial adenomatoid hamartoma, inverted papilloma, and intestinal-type and non-intestinal type sinonasal adenocarcinoma; an immunohistochemical study. Arch Pathol Lab Med 2007;131:530-537.
View Dr. Ozolek's full list of publications from PubMed.
Research Interests
My main research interest is developing cellular therapies to treat premature infant brain injury due to neuronal and glial cell death prompted by hypoxia and ischemia in the newborn period. To this end, we have established protocols for differentiating embryonic stem cells into primarily neuronal and glial phenotypes, and have characterized their proliferation, apoptotic activity, and capability to differentiate under several conditions in culture. We have also demonstrated movement and differentiation of embryonic stem cells in vivo. A related research interest includes characterizing expression of stem cell markers in childhood tumors that show pluripotentiality. Other interests include using protein expression and molecular techniques to understand the pathogenesis of primitive neuroectodermal and neuroblastic tumors and myofibroblastic lesions in children. Current studies are underway to characterize subsets of enteric ganglion cells at various stages of development and in pathologic conditions.
