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Jerome Parness, MD, PhD

Job Title Visiting Professor, University of Pittsburgh School of Medicine
Job Title Visiting Professor, University of Pittsburgh Medical Center
4401 Penn Avenue
Pittsburgh, PA 15224
412-692-5260 Phone
412-692-8658 Fax

Education and Training

Medical School:

1982 PhD, Sue Golding Graduate Division, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY
1985 MD, Albert Einstein College of Medicine, Bronx, NY


1989 Hospital of the University of Pennnsylvania, Philadelphia, PA


1982 Albert Einstein College of Medicine, Bronx, NY
1985 Research, Weizmann Institute of ScienceAlbert Cass, Rehovot Israel
1989 Children’s Hospital of Philadelphia, Philadelphia, PA


  • Malignant Hyperthermia Association of the United States, Hotline Consultant     
  • Society for Pediatric Anesthesia, Research Committee

Board Certifications

  • American Board of Anesthesiology


  • 1995-1997 Anesthesiology Young Investigator Award, Foundation for Anesthesia Education and Research              
  • Albert Cass Traveling Fellowship (Research)                 
  • Alpha Omega Alpha, National Medical Honor Society             
  • Ben-Gurion International Exchange Fellowship, Ben-Gurion University, Beersheba, Israel
  • 1972-74 Graduate Student Incentive Award, Eshkol Fund, Israel National Council for Research and Development
  • 1971-74 Graduate Student Study Prize, The Hebrew University Faculty of Science and Mathematics


  • Zhao, X., Weisleder, N., Han, X., Pan, Z., Parness, J.*, Brotto, M.*, Ma, J. Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor. J Biol Chem 2006; 281(44):3477-86.  *Co-corresponding authors.
  • Luty, W., Rodeberg, D., Parness, J., Vyas, Y.  Antiparallel segregation of Notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates.  Journal of Immunology, 2007;179:819-29.
  • Liang, X., Parness, J., Fruen, B., Hu, J., Hu, X., Ma, J.  Tight coupling of skeletal muscle ryanodine receptors is abrogated in malignant hyperthermia.  Manuscript submitted.

    View Dr. Parness' full list of publications from PubMed.

Research Interests

  • The Mechanism of Action of Dantrolene
  • Molecular Mechanisms in the Genesis of Malignant Hyperthermia
  • Skeletal Muscle Excitation-Contraction Coupling
  • Ryanodine Receptor-Dependent Intracellular Calcium Regulation
  • Store Operated Calcium Entry
  • Notch and WASp Signaling in T-helper Cell Development
Last Update
April 28, 2009
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Last Update
April 28, 2009