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Physician Profile

412-692-6795 Phone
412-692-5228 Fax

Edward V. Prochownik, MD, PhD

Job Title Director of Oncology Research, Children's Hospital of Pittsburgh
Job Title Professor of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine
4401 Penn Avenue, Suite Floor 9
Pittsburgh, PA 15224
412-692-6795 Phone
412-692-5228 Fax

Education and Training

Medical School:

1978 The University of Chicago Pritzker School of Medicine, Chicago, Ill.


1980 Children's Hospital of Boston, Boston, Mass.


1983 Children's Hospital of Boston Dana Farber Cancer Institute, Boston, Mass.


  • American Pediatric Society
  • American Society for Clinical Investigation
  • American Society of Hematology
  • American Society for Microbiology
  • Society for Pediatric Research

Board Certifications

  • American Board of Pediatrics
  • Pediatric Hematology/Oncology


  • Yap JL, Wang H, Hu A, Chauhan J, Jung KY, Gharavi RB, Prochownik EV, Fletcher S. Pharmacophore identification of c-Myc inhibitor 10074-G5. Bioorg Med Chem Lett. 2013 Jan 1;23(1):370-4.
  • Kim SY, Rhee JG, Song X, Prochownik EV, Spitz DR, Lee YJ. Breast cancer stem cell-like cells are more sensitive to ionizing radiation than non-stem cells: role of ATM. PLoS One. 2012;7(11):e50423.
  • Zhang F, Rothermund K, Gangadharan SB, Pommier Y, Prochownik EV, Lazo JS. Phenotypic screening reveals topoisomerase I as a breast cancer stem cell therapeutic target. Oncotarget. 2012 Sep;3(9):998-1010.

Research Interests

  • Function and pharmacologic regulation of the c-Myc oncoprotein
  • Impact of c-Myc oncoprotein expression on cellular metabolism

Active Research Projects / Grants

  • Primary Investigator, Evaluation of molecular inhibitors of the c-myc oncoprotein
  • Primary Investigator, Regulation of and by the Myc oncoprotein
Last Update
November 23, 2014
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Last Update
November 23, 2014