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Vincent Schmithorst, PhD

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Job Title Visiting Associate Professor of Radiology, Department of Radiology, University of Pittsburgh School of Medicine
4401 Penn Avenue, Suite Floor 2
Pittsburgh, PA 15224
412-692-3212 Phone
412-692-6312 Fax

Education and Training

Graduate School:

1997 PhD University of Cincinnati, Ohio


  • International Society for Magnetic Resonance in Medicine
  • Organization for Human Brain Mapping


  • 2006 Editors Choice Award, presented by the Organization for Human Brain Mapping for Best Paper in the Cognitive Neuroscience Section of NeuroImage


  • Tkach JA, Chen X, Freebairn LA, Schmithorst VJ, Holland SK, Lewis BA. Neuralcorrelates of phonological processing in speech sound disorder: A functionalmagnetic resonance imaging study. Brain Lang. 2011 Mar 31. [Epub ahead of print] PubMed PMID: 21458852.
  • Schmithorst VJ, Holland SK, Plante E. Diffusion tensor imaging reveals whitematter microstructure correlations with auditory processing ability. Ear Hear.2011 Mar-Apr;32(2):156-67. PubMed PMID: 21063207; PubMed Central PMCID:PMC3057932.
  • Karunanayaka P, Schmithorst VJ, Vannest J, Szaflarski JP, Plante E, HollandSK. A linear structural equation model for covert verb generation based onindependent component analysis of FMRI data from children and adolescents. Front Syst Neurosci. 2011;5:29. Epub 2011 Jun 1. PubMed PMID: 21660108; PubMed Central PMCID: PMC3106180.

    View Dr. Schmithorst's full list of publications from PubMed.

Research Interests

  • Functional MRI of hearing-impaired pediatric subjects.  I have developed silent fMRI techniques suitable for use in the hearing-impaired pediatric population.  I am interested in using them to investigate cortical reorganization following unilateral hearing loss, as well as the suitability of fMRI as a preoperative indicator for cochlear implantation in patients with severe-to-profound bilateral sensorineural hearing loss.
  • Auditory Processing Disorder. I am interested in investigating the etiology and neurobiological underpinnings of APD in children using functional MRI.  Current research suggests APD may in fact be more of a cognitive than a sensory disorder; if this is confirmed using neuroimaging techniques, this result will have profound implications for diagnosis and management strategies.
  • White matter microstructure in the pediatric population. I am interested in investigating the normal development of white matter as well as its correlates with intelligence and other measures of cognitive function.
  • Novel image analysis techniques for use on neuroimaging data. I have extensively utilized Independent Component Analysis (ICA), a data-driven method, as a complementary technique to conventional hypothesis-driven methods such as the General Linear Model (GLM) for analysis of fMRI data.  I aim to use machine-learning techniques (multivariate pattern analysis) to enable functional MRI data (and other MRI data such as diffusion) to predict psychological and other pathologies, as well as outcomes.

Active Research Projects / Grants

  • Cortical Reorganization in Children with Unilateral Sensorineural Hearing Loss
  • Pediatric Functional Neuroimaging Research Network
Last Update
February 9, 2012
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Last Update
February 9, 2012