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Robert Squires, Jr., MD

Dr. Robert Squires, Jr. - Clinical Director, Division of Pediatric Gastroenterology
Job Title Division of Pediatric Gastroenterology
Job Title Professor of Pediatrics, University of Pittsburgh School of Medicine
4401 Penn Avenue, Suite Floor 3
Pittsburgh, PA 15224
412-692-5180 Phone
412-692-7355 Fax

Education and Training

Medical School:

1981 University of Texas Medical Branch Division, Galveston


1980 St. Louis Children's Hospital, MO


1981 Pediatric Gastroenterology/Nutrition, St. Louis Children's Hospital, Barnes Hospital, Jewish Hospital, VA Hospital, St. Louis, MO
1981 Ambulatory Pediatrics, St. Louis Children's Hospital, MO


  • American Academy of Pediatrics
  • North American Society of Pediatric Gastroenterology, Hepatology and Nutrition
  • American Gastroenterological Association


  • Squires RH Jr, Shneider BL, Bucuvalas J, Alonso E, Sokol RJ, Narkewicz MR, Dhawan A, Rosenthal P, Rodriguez-Baez N, Murray KF, Horslen S, Martin MG, Lopez MJ, Soriano H, McGuire BM, Jonas MM, Yazigi N, Shepherd RW, Schwarz K, Lobritto S, Thomas DW, Lavine JE, Karpen S, Ng V, Kelly D, Simonds N, Hynan LS. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr. 2006 May;148(5):652-658.
  • Fuda F, Narayan SB, Squires RH Jr, Bennett MJ. Bile acylcarnitine profiles in pediatric liver disease do not interfere with the diagnosis of long-chain fatty acid oxidation defects. Clin Chim Acta. 2006 May;367(1-2):185-8. Epub 2006 Jan 18.
  • Bucuvalas J, Yazigi N, Squires RH Jr. Acute liver failure in children. Clin Liver Dis. 2006 Feb;10(1):149-68, vii. Review.

Research Interests

  • Acute liver failure in children - NIH-sponsored
  • Biliary atresia and neonatal cholestasis - NIH-sponsored
  • Lipid abnormalities in intestinal transplant patients
  • Hepatocyte transplantation

Biography Summary

Robert H. Squires Jr., MD, joined Children's Hospital of Pittsburgh as clinical director, Division of Pediatric Gastroenterology, and director of Hepatology in 2003, bringing to the hospital extensive experience in pediatric gastroenterology, expertise in pediatric liver disease and an interest in helping children with liver disease avoid transplantation.

Dr. Squires completed his undergraduate work in his native Texas, earning a bachelor's degree from Austin College in Sherman. In 1977, he earned his medical degree from the University of Texas Medical Branch in Galveston. He completed his internship and residency in pediatrics at St. Louis Children's Hospital, Washington University in St. Louis, where he also served as chief resident in pediatrics and completed fellowships in pediatric gastroenterology, nutrition and ambulatory pediatrics.

Five years after establishing a private practice in pediatric gastroenterology in Ft. Worth, Texas, he was recruited to develop a clinical program at Children's Medical Center in Dallas and to teach at the University of Texas Southwestern Medical School. He was a professor of pediatrics and the director of hepatology and medical director of the Liver Transplant Program at Children's Medical Center when he left to join Children's Hospital of Pittsburgh. In addition to his work at the hospital, he is a professor of pediatrics at the University of Pittsburgh School of Medicine.

Dr. Squires served as chair of the Gastroenterology Section of the American Academy of Pediatrics and was an executive council member of the North American Society for Pediatric Gastroenterology Hepatology and Nutrition. His research interests include fatty liver disease of childhood, clinical aspects of hepatocyte transplantation, hepatitis B and C, medical aspects of liver transplantation, and neonatal cholestasis. Dr. Squires is a national primary investigator for the National Institutes of Health-funded Pediatric Acute Liver Failure Study and is developing treatment plans for children with the disease. He is also a member of the NIH-funded Biliary Atresia Research Consortium, a national study of the serious disorder that prevents bile from leaving the liver of afflicted infants.

Clinical Specialties

  • Pediatric liver disease
  • Hepatitis B and C
  • Medical aspects of liver and intestinal transplantation
  • Acute liver failure
  • Autoimmune hepatitis
  • Cholestasis and metabolic liver disease
  • Biliary atresia
Last Update
July 7, 2015
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Last Update
July 7, 2015