Research

Childhood Metabolic Markers Study

Childhood Metabolic Markers of Adult Morbidity in Blacks

Protocol Description

The purpose of this study is to determine why black American children are at a higher risk than white American children for developing obesity, type-2 diabetes, high blood pressure, and heart disease. It is theorized that insulin action is lower in black Americans, and in response, the body produces more insulin, leading to possible increased risk for the development of diabetes and obesity. Long term goals of the study are to develop prevention strategies to improve the health care of black Americans.

Eligibility Criteria

The study is currently accepting healthy black American or white American males and females, who are normal weight or overweight, and between 8 and 17 years.
Boys: 8 to 17 years
Girls: 8 to 17 years

Requirements
In addition to the screening process, participants will be admitted for 2 times to Children’s Hospital of Pittsburgh of UPMC for a 24 hour overnight stay in which tests and procedures will be performed to determine body composition and metabolism including insulin secretion and sensitivity. The costs related to the admissions are not the responsibility of the parents or insurance and will be covered by grants.
Visits: 2 overnight stays
Duration: Up to 3 weeks

Status: Open for Enrollment

Source of Support
Pediatric Clinical and Translational Research Center
National Institutes of Health