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Clinical Studies and Research

Opening doors to new treatments.

Children’s Hospital’s Brain Care Institute is a leader in neurological research and has made major discoveries in understanding the genetic, molecular, cellular, and organizational bases for many of these conditions. Faculty members in the Brain Care Institute receive more than $1 million in federal corporate and foundation research funding each year to continue studying these disorders.

Current research and clinical trials in the area of neurofibromatosis include:

  • How plexiform neurofibroma (PNF) tumors respond to weekly dosages of Peginterferon alfa-2b (also known as PEG-Intron), a long-acting form of interferon
  • Exploring the side effects of Peginterferon alfa-2b and evaluating “volumetric analysis,” a new method of measuring changes in tumor size using magnetic resonance imaging (MRI) scans
  • Refining the use of genetics to diagnose Neurofibromatosis
  • Incidence of migraine headache in the NF population
  • Mood disorders in the NF population
  • Natural history of optic glioma studies
Last Update
March 5, 2012
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Last Update
March 5, 2012