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Faculty Research Activities
- Principal Investigator, Children’s Oncology Group studies at Children’s Hospital if Pittsburgh
- Hemostasis research, especially clinical thrombosis
- Co-principal investigator of the phase I Consortium of the Children's Oncology Group, which conducts early phas clinical trials of novel agents in pediatric oncology.
- Quality improvement analysis aimed at Improving the Scope and Quality of Bereavement Care for Families who have Suffered the Loss of a Child to Cancer.
- Project aimed at Advancing Peditatric Resident Education in Pediatric Palliative and End-of-Life Care and Communication.
- Comparison of Thrombosis Rates in Adolescent and Young Adult (AYA) Versus Younger Pediatric Oncology Patients.
- Understanding the genetic variation and outcome of bone marrow transplantation, especially graft-versus-host-disease
- Focuses on understanding of some of the cellular modifications induced by overexpression of the c-Myc oncoprotein that ultimately result in development of tumors.
- Institutional principal investigator for an industry sponsored clinical trial titled "Pilot study for standardization of diagnostic techniques for central venous catheters - Venous Thromboembolism Study".
- Characterization of microRNA expression of platelets in Sickle Cell Disease.
- Storage lesions in banked blood due to disruption of Nitric Oxide (NO) homeostasis.
- Clinical neuro-oncology research through Children’s Oncology Group, Pediatric Brain Tumor Consortium and pharmaceutical investigations
- Principal Investigator of the phase I consortium at Children’s Hospital of Pittsburgh
- Curing sickle cell disease through non-myeloablative bone marrow transplantation
- Enhance delivery of care to patients and carriers with sickle disease or trait
- Pediatric Resident Palliative Care Curriculum
- Measuring Practice Patterns of Withdrawal of Nonbeneficial Therapies in Pediatric ICU
- Feasibility and Effectiveness of a Comprehensive Bereavement Program for Families Whose Children have Died from Cancer
- Understanding the role of Myc oncoproteins in normal and malignant cell growth
- Manipulation of umbilical cord and peripheral blood stem cells to increase platelet precursors to improve platelet recovery following stem cell transplantation
- Clinical oncology research
- Rituximab in the treatment of opsoclonus monoclonus syndrome
- Late effects in childhood cancer
- Delineating the Molecular Pathogenesis of the life-threatening disease of childhood Wiskott-Aldrich Syndrome (WAS).
Last Update
December 21, 2012
December 21, 2012
