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The purpose of this study is to find out the levels of vitamin D associated with vitamin D insufficiency (low vitamin D status) in school-age children. Results will help to show prevalence of low vitamin D levels in children and how vitamin D levels affect their bone health. Vitamin D is important for keeping bones healthy and strong. Vitamin D is produced by the body when sunlight touches the skin. In the northern United States, in places such as Pittsburgh, the potential for vitamin D insufficiency is greater during winter because of reduced exposure to sunlight. Vitamin D levels may be lower among people with darker skin. Dark skinned individuals have more melanin in their skin, and melanin acts as a natural sunscreen. Vitamin D insufficiency during childhood has the potential to impact an individual’s achievement of peak bone mass.
This study will enroll healthy Caucasian and African-American children of both genders, ages 8 to 14.
Boys: Ages 8 to 14 years
Girls: Ages 8 to 14 years
Participants will complete 3 office visits over a 6-month period. Study visits will include physical examination for assessment of pubertal status, estimation of skin color, blood draws, assessment of calcium and vitamin D intake and sunlight exposure. Participants will be randomly assigned to take a vitamin D pill or placebo daily for the duration of the study, and parents will need to provide a 3-day record of their child’s food and beverage intake.
Duration: 6 months
National Institutes of Health
Study Description at National Institutes of Health
Kumaravel Rajakumar, MD
To get started, please contact:
Kumaravel Rajakumar, MD
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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