Children's Hospital is part of the UPMC family.
Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration
JW Yester, B Kühn
Current Cardiology Reports
Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth
B. Ganapathy, N. Nandhagopal, B. Polizzotti, D. Bennett, A. Asan, Y. Wu, B. Kühn
2016 May 13
A cryoinjury model in neonatal mice for cardiac translational and regeneration research
BD Polizzotti, B Ganapathy, BJ Haubner, JM Penninger, B. Kühn
Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window (PDF)
BD Polizzotti, B Ganapathy, S Walsh, S Choudhury, N Ammanamanchi, DG Bennett, CG dos Remedios, BJ Haubner, JM Penninger, B. Kühn
Science Translational Medicine
2015 Apr 1
Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation (PDF)
SE Senyo, RT Lee, B Kühn
Stem Cell Research
Muscling Up the Heart - A Preadolescent Cardiomyocyte Proliferation Contributes to Heart Growth
CH Zhang, B Kühn
2014 Sep 26
New mechanistic and therapeutic targets for pediatric heart failure: report from a national heart, lung, and blood institute working group (PDF)
KM Burns, BJ Byrne, BD Gelb, B Kühn, LA Leinwand, S Mital, GD Pearson, M Rodefeld, JW Rossano, BL Stauffer, MD Taylor, JA Towbin, AN Redington
2014 Jul 1
Signalling between microvascular endothelium and cardiomyocytes through neuregulin (PDF)
EM Parodi, B Kühn
2014 May 1 (Epub 2014 Jan 29)
Moderate and high amounts of tamoxifen in α-MHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death (PDF)
K Bersell, S Choudhury, M Mollova, BD Polizzotti, B Ganapathy, S Walsh, B Wadugu, S Arab, B Kühn
Disease Models & Mech
2013 Nov (posted online 2013 Aug 7)
Cardiomyocyte proliferation contributes to heart growth in young humans (PDF)
M Mollova, K Bersell, S Walsh, J Savla, LT Das, SY Park, LE Silberstein, CG Dos Remedios, D Graham, S Colan, B Kühn
2013 Jan 22
Intrapericardial delivery of gelfoam enables the targeted delivery of periostin peptide after myocardial infarction by inducing fibrin clot formation (PDF)
BD Polizzotti, S Arab, B Kühn
2012 May 10
The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation (PDF)
B Wadugu, B Kühn B
Am J Physiol Heart Circ Physiol
2012 Mar 16
Taking the load off: Nuclear remodeling after mechanically supporting the failing human heart (PDF)
C Murry, B Kühn
2010 Mar 2
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury (PDF)
K Bersell, S Arab, B Haring, B Kühn
2009 Jul 24
Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair (PDF)
B Kühn, F Del Monte, RJ Hajjar, YS Chang, D Lebeche, S Arab S, et al.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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