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Jerome Parness, MD, PhD

Job Title Visiting Professor, University of Pittsburgh School of Medicine
Job Title Visiting Professor, University of Pittsburgh Medical Center
4401 Penn Avenue
Pittsburgh, PA 15224
412-692-5260 Phone
412-692-8658 Fax

Education and Training

Medical School:

1982 PhD, Sue Golding Graduate Division, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY
1985 MD, Albert Einstein College of Medicine, Bronx, NY

Residency:

1989 Hospital of the University of Pennnsylvania, Philadelphia, PA

Fellowship:

1982 Albert Einstein College of Medicine, Bronx, NY
1985 Research, Weizmann Institute of ScienceAlbert Cass, Rehovot Israel
1989 Children’s Hospital of Philadelphia, Philadelphia, PA

Memberships

  • Malignant Hyperthermia Association of the United States, Hotline Consultant     
  • Society for Pediatric Anesthesia, Research Committee

Board Certifications

  • American Board of Anesthesiology

Awards

  • 1995-1997 Anesthesiology Young Investigator Award, Foundation for Anesthesia Education and Research              
  • Albert Cass Traveling Fellowship (Research)                 
  • Alpha Omega Alpha, National Medical Honor Society             
  • Ben-Gurion International Exchange Fellowship, Ben-Gurion University, Beersheba, Israel
  • 1972-74 Graduate Student Incentive Award, Eshkol Fund, Israel National Council for Research and Development
  • 1971-74 Graduate Student Study Prize, The Hebrew University Faculty of Science and Mathematics

Publications

  • Zhao, X., Weisleder, N., Han, X., Pan, Z., Parness, J.*, Brotto, M.*, Ma, J. Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor. J Biol Chem 2006; 281(44):3477-86.  *Co-corresponding authors.
  • Luty, W., Rodeberg, D., Parness, J., Vyas, Y.  Antiparallel segregation of Notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates.  Journal of Immunology, 2007;179:819-29.
  • Liang, X., Parness, J., Fruen, B., Hu, J., Hu, X., Ma, J.  Tight coupling of skeletal muscle ryanodine receptors is abrogated in malignant hyperthermia.  Manuscript submitted.

    View Dr. Parness' full list of publications from PubMed.

Research Interests

  • The Mechanism of Action of Dantrolene
  • Molecular Mechanisms in the Genesis of Malignant Hyperthermia
  • Skeletal Muscle Excitation-Contraction Coupling
  • Ryanodine Receptor-Dependent Intracellular Calcium Regulation
  • Store Operated Calcium Entry
  • Notch and WASp Signaling in T-helper Cell Development
Last Update
April 28, 2009
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Last Update
April 28, 2009
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