Fernando Holguin, MD


Medical Director, Pediatric Environmental Medicine Center, University of Pittsburgh, Children’s Hospital of Pittsburgh of UPMC
Assistant Professor of Medicine, University of Pittsburgh
Associate Researcher, National Institute of Public Health, Mexico
Stars 5 35 Patients Satisfaction Reviews 9 comments

Internal Medicine

Secondary Specialty:

Critical Care

Board Certifications:

Pulmonary Disease, Critical Care Medicine


LaSalle University
Mexico City,


Emory University School of Medicine
Atlanta, GA
Emory University School of Medicine
Atlanta, GA


UPMC Presbyterian
Magee-Womens Hospital of UPMC
Children's Hospital of Pittsburgh of UPMC




Research Interests

  • A randomized, placebo-controlled study of pioglitazone to treat poorly controlled obese asthmatics
  • Effect of a dietary weight loss intervention on airway oxidative stress, asthma control and lung function in a cohort of asthmatic children in Mexico City
  • Airway adipokines and alveolar macrophage PPARγ expression. A link between obesity and airway oxidative stress in asthma
  • A randomized pilot study to evaluate the effects of pioglitazone and standard therapy vs placebo and standard therapy to treat obese, uncontrolled asthmatics
  • Effects of weight loss on airway inflammation and oxidation in asthmatic subjects undergoing bariatric surgery
  • Virtual reality skills training: nicotine dependence
  • The role of leukotrienes in the asthma obesity phenotype
  • Effects of air pollution on the respiratory health of children with Sickle Cell Disease in Atlanta
  • The role of chronic alcohol consumption in airway oxidative stress in patients with and without asthma
  • A bi-national study of asthma and air pollution in children in the US-Mexico border
  • Effects of air pollution on cardiovascular disease
  • Defining the mechanisms by which obesity leads to an increase risk for asthma
  • Understanding disparities in pulmonary health outcomes at a national level

View Dr. Holguin's full list of publications from PubMed.

Patient Comments

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Total Comments: 9


Locations and Directions

  • Division of Pulmonary, Allergy & CCM

    Falk Medical Building

    3601 Fifth Ave.
    4th Floor
    Pittsburgh, PA 15213
    (412) 648-6161

  • Pediatric Pulmonology

    Children's Hospital of Pittsburgh of UPMC

    4401 Penn Ave.
    3rd Floor
    Pittsburgh, PA 15224
    (412) 692-5661