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Amr H. Sawalha, MD
Professor and Chief, Division of Pediatric Rheumatology
Director, Lupus Center of Excellence
University of Pittsburgh Medical School
UPMC Children's Hospital of Pittsburgh
Brief Summary of Lecture
The etiology of autoimmune diseases is incompletely understood, and both genetic and environmental factors are thought to play a role in disease pathogenesis. Over the last decade, significant progress has been made in uncovering the genetic basis of autoimmune diseases. Dr. Sawalha will discuss basic principles and progress made in understanding genetic susceptibility to complex human diseases. He will demonstrate, using examples from lupus and systemic vasculitis, how genetics can help understand disease pathogenesis, and provide avenues for translational insight. He will also discuss the complexity of the human genome and highlight using recent examples from his laboratory the need for functional genomic studies to understand pathological consequences of disease susceptibility loci in autoimmunity.
Date and Time: Thursday, June 27, 8-9 a.m.
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UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
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