Cystic Fibrosis Center

The Antonio J. and Janet Palumbo Cystic Fibrosis Center (CF Center) at Children's Hospital of Pittsburgh of UPMC is dedicated to providing state-of-the-art care to patients and families with cystic fibrosis, education for health care professionals, and conducting clinical and basic research in cystic fibrosis. The program is accredited by the Cystic Fibrosis Foundation for clinical care and research. Based on consistently good patient outcomes, our CF Center recently was selected as a benchmarking site, from which other programs could learn from our practices.

The pediatric program cares for approximately 280 patients, and nearly 200 patients are seen in the adult program. Pediatric patients are seen in any of four locations (including the main hospital in Lawrenceville, Children's North, Children's South, and Children's East). Our team includes board-certified pediatric pulmonologists, registered dietitians, nurses, social workers, and respiratory therapists, as well as administrative support staff. Our extended team includes representatives from gastroenterology, endocrinology, and medical genetics. A pediatric pulmonologist experienced in cystic fibrosis is available 24 hours a day.

Read our special newsletter with new inpatient and clinic guidelines (PDF).

Our multidisciplinary clinical services include evaluation, diagnosis, and treatment, including emphasis on promoting normal growth and development, slowing the progression of the illness, preventing and treating complications, and helping the family integrate even the most complex care regimens into their daily lives.

Rachel, a patient of the Antonio J. and Janet Palumbo Cystic Fibrosis Center at Children’s Hospital, is a student at Johns Hopkins University.

Education and Training Program

Training tomorrow's pediatric pulmonologists is an important part of the mission of the Cystic Fibrosis Center as part of the Division of Pediatric Pulmonary Medicine, Allergy and Immunology. The division takes full advantage of its strengths to provide educational opportunities that are second to none, including a fellowship program that offers comprehensive training in both the clinical and research aspects of pulmonary medicine.

Learn more.

A Leader in Pediatric Medicine

Children’s Hospital of Pittsburgh of UPMC is a recognized leader in pediatric medicine. Quality patient care and advanced research consistently place Children’s among the nation's top pediatric hospitals as reported by U.S. News & World Report. In May 2009, Children's relocated to its new, state-of-the-art campus, which includes a new hospital and the 300,000-square-foot John G. Rangos Sr. Research Center.

Learn more about Children's Hospital campus.

Read "For 13-year-old, Robert Morris lacrosse teammates are 'all my older brothers'" (Pittsburgh Post-Gazette article).



Clinical Studies

David Orenstein, MD

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Daniel Weiner, MD

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Joseph Pilewski, MD

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Joel Weinberg, MD

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Shean Aujla, MD

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Sangeeta Chakravorty, MD, Dip. ABSM

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Jonathan Finder, MD

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Jay Kolls, MD

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Geoffrey Kurland, MD

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Michael Myerburg, MD

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Jonathan Spahr, MD

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  • Antonio J. and Janet Palumbo Cystic Fibrosis Center (CF Center)

    Children's Hospital of Pittsburgh of UPMC
    4401 Penn Avenue
    Floor 3
    Pittsburgh PA, 15224

  • CF Patient Registry

    Participation in the Cystic Fibrosis Patient Registry Read more

    Cystic Fibrosis, Aspergillosis and the Effect of Vitamin D

    Open-label Vitamin D Trial for Patients with Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis Read more

    Cystic Fibrosis and the Effects of Inhaled Bicarbonate

    Effects of Inhaled Bicarbonate on Airway pH in Cystic Fibrosis Read more

    Genetic Modifiers of Cystic Fibrosis

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    Immunological Factors of Lung Functions

    Mechanisms of Immune Tolerance and Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) in Patients with Cystic Fibrosis Read more

    The EPIC Observational Study

    The EPIC Observational Study: Long-Term Study of Risk Factors and Impact of Pseudomonas aeruginosa and Early Anti-Pseudomonal Treatment in Children with Cystic Fibrosis Read more