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This multi-center study investigates the safety and therapeutic benefit of long-term treatment using the Viaskin Peanut 250 microgram drug patch to help children with peanut hypersensitivity. The use of a patch to deliver a peanut protein antigen to desensitize patients against allergic reactions is called epicutaneous immunotherapy, or EPIT. In the U.S., peanut hypersensitivity prevalence is growing, and among food allergies, peanut allergy is the most common cause of death.
This study is open to participants of both genders, who were previously enrolled in a 12-month precursor investigation (the PEPITES study), and it extends their participation for a total of 3 years on the patch.
Boys and girls: Ages 5 through 12 years
In this study, participants will use the Viaskin Peanut 250 microgram patch for 2 additional years, if they used the Viaskin patch in the PEPITES study, or for 3 years if they used a placebo patch. During this study, researchers will contact parents/guardians at specific intervals by telephone, and study visits will be required for physical exams and testing, including blood work, allergen skin tests, and pulmonary function tests.
Visits: 9 to 12, dependent on whether participants received a placebo in the prior study
Duration: 25 to 36 months
Study Description at National Institutes of Health
Hey Jin Chong, MD, PhD
For more information about the study or enrollment, please contact:
Clinical Research Coordinators
Linette Milkovich, RN
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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