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This multicenter study is being done to test the application of the CP Stent™, an uncovered platinum-iridium wire stent, also known as the Cheatham platinum stent, for treatment of coarctation of the aorta (CoA). CoA is a narrowing of the aorta, the body’s main blood vessel. The initial study, begun in 2007, has achieved its maximum intended enrollment, however the Food and Drug Administration has extended use of the CP Stent based on certain proven advantages over stainless steel versions, such as compatibility with magnetic resonance imaging and easy visualization via x-ray and fluoroscopy.
A physician’s referral is required for this study, which is open to children and teens who have native or recurrent CoA.
Males and Females: Ages 8 to 80
Using standard medical practice for this condition, a balloon-tipped catheter will be inserted through the blood vessel positioned across the aortic coarctation and inflated with low pressure to stretch the narrowed portion. If the area stretches well enough, the CP Stent will be used and the child will be admitted into the study. Follow-up visits will occur at 1 month, 6 months and annually thereafter for 5 years.
Visits: Requires hospitalization; then, follow-up visits
Duration: 6 years
Johns Hopkins University
Study Description at National Institutes of Health
Jacqueline Kreutzer, MD, FACC, FSCAI
For information, please contact:
Kelli Shepler, CRC
Jane Luce, MPH, CHES
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
Children’s Hospital of Pittsburgh of UPMC
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.