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This multi-center study evaluates the ability of an investigational diagnostic test to identify the cause of respiratory infections. Currently, no single test can quickly determine if a child’s respiratory symptoms and illness are due to a virus, bacteria, fungus or not caused by an infection at all. Using samples collected during the medical evaluation, researchers will study gene expression – examining how genes are turned on or off in response to the illness – seeking patterns that can lead to effective diagnoses.
Pediatric patients being evaluated in the Emergency Room of UPMC Children’s Hospital of Pittsburgh with symptoms of acute respiratory illness are eligible to participate.
Males and Females: Ages 2 years and up
Blood and urine samples will be collected, and a nasal or throat swab may also be collected. Samples will be sent to a lab for analysis along with medical record information and will not be used in connection with immediate treatment for the child’s condition. Researchers will follow up within 12 months to check patient response to treatment.
Visits: None beyond normal treatment for these conditions
Duration: 12 months
National Institutes of Health
Host Response, Inc.
Respiratory Problems, Age 11 and Younger
Respiratory Problems, Age 12 and Older
Emergency Medicine Research
Robert W. Hickey, MD
For more information about the study or enrollment, please contact:
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.