Neuroblastoma Biology Studies

Protocol Description

The purpose of this Children's Oncology Group multi-center observational study is to learn more about neuroblastoma and gain a better understanding of the genes that control neuroblastoma growth. The study involves the collection of tissues, such as the neuroblastoma tumor, and blood and/or bone marrow obtained during medical procedures. Tissue obtained will be subject to specialized laboratory testing to assess genetic information and analyze chromosomal abnormalities with a goal of providing a better understanding of prognosis for patients with neuroblastoma.

Eligibility Criteria

Subject to certain exclusion criteria, this study is enrolling patients and newly diagnosed with suspected neuroblastoma or ganglioneuroblastoma, who are preparing to undergo a biopsy, a resection or a clinical procedure.
Males and Females: Any age

Requirements

Participants will be asked for permission to use samples of their tumor, blood and/or bone marrow to help researchers learn more about neuroblastomas. All samples will be obtained at the time of surgery or from standard clinical procedures, and only residual samples will be used for this research study.
Visits: Not applicable
Duration: Not applicable

Status: Open to Enrollment

Source(s) of Support

Children’s Oncology Group (Study ANBL00B1)
National Cancer Institute

Additional Information

Study Description at the National Institutes of Health
Cancer and Blood Disorder Research 

Primary Investigator

Jean M. Tersak, MD

Contact Information

For more information about the study, please contact the UPMC Children’s Hospital of Pittsburgh Hematology-Oncology research team, at: HOCHPPhaseIII@upmc.edu.