Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #8 Nationally by U.S. News & World Report.
The purpose of this research study is to compare the two most common surgical treatments for Chiari type I malformation with syringomyelia (CM+SM): posterior fossa decompression (PFD) or PDF with duraplasty (PFDD). The fundamental difference between the two approaches is that PFDD also surgically opens the dura, the thickest and strongest of the three linings of the central nervous system. Researchers will evaluate each approach in terms of effectiveness, quality of life, and surgical complications.
This study is enrolling male and females through age 21, diagnosed with CM+SM who will be undergoing surgical treatment for their condition.
Males and Females: Through age 21
Through random selection participants will receive either the PFD or PFDD surgical treatment. Participants will be followed at specific intervals for up to 14 months after surgery, as is required for standard care for a procedure of this type. Information about patients’ health and response to treatment will be collected along with quality of life information that will assess cognitive, psychosocial, and physical symptoms.
Visits: None beyond normal clinical care
Duration: Up to 14 months
Washington University School of Medicine
Patient-Centered Outcomes Research Institute
Study Description at National Institutes of Health
Stephanie Greene, MD, PHD
For more information about the study or enrollment, please contact:
Kimberly Diamond, BS, BA
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.