Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Download our mobile app today - it's free!
The main objective of this study is to determine benefits of feeding premature babies with milk while they are receiving indomethacin or ibuprofen for treatment for patent ductus arteriosus (PDA), a condition in which a connecting blood vessel between the aorta and pulmonary artery stays open after birth creating circulation problems. The present standard of care for infants with PDA is intravenous treatment with indomethacin or ibuprofin, and most neonatologists withhold feedings during this therapy. Researchers hypothesize that feeding preterm infants during therapy will decrease the incidence of feeding intolerance and shorten the time infants need to tolerate full enteral nutrition.
To be considered for the study, infants must be admitted to the Neonatal Intensive Care Unit of Magee-Womens Hospital and be less than 31 weeks gestational age and have a birth weight of 401 to 1250 grams (14 ounces to 2.75 pounds), receiving or are scheduled to begin oral feedings, and about to receive pharmacologic treatment to close their PDA.
Boys: Less than 31 weeks, gestational age
Girls: Less than 31 weeks, gestational age
Enrolled infants will be randomly assigned one of the two study medications and whether or not oral feedings will be provided during the drug therapy. Echocardiograms and ultrasound procedures will also be done.
Visits: None beyond normal clinical care
Duration: Not applicable
Study description at National Institutes of Health
Toby Debra Yanowitz, MD
Robyn Baker, BSN, CRNP
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.