Craniofacial Disorder Analysis Through Medical Imaging

Advanced Craniofacial Radiographic Analysis

Protocol Description

The purpose of this study is to model normal and abnormal craniofacial growth and development in patients with and without congenital and acquired disorders of the craniofacial skeleton and to quantify the degree of deformity and to detect possible complications that may follow, such as intracranial hypertension, to allow for better disease stratification, operative planning and timely intervention. The study uses review of medical records and computed tomography (CT) and magnetic resonance imaging (MRI) scans.

Eligibility Criteria

Pediatric patients who have been evaluated by the UPMC Children’s Hospital of Pittsburgh Plastic Surgery Division’s Cleft and Craniofacial Center and Neurosurgery Divisions will be eligible to participate, providing that high-quality CT/MRI scans were done and that the patients’ medical conditions align with other inclusion criteria.
Males and Females: All ages

Requirements

Researchers will compare age-matched scans of patients with congenital and acquired craniofacial anomalies to scans of patients with no structural abnormality, enabling researchers to create a stratification tool for diagnosis and treatment of craniofacial disease.
Visits: None beyond normal treatment for these conditions
Duration: Not applicable

Status: Open to Enrollment

Additional Information

Plastic Surgery Research

Primary Investigator

Jesse Goldstein, MD

Contact Information

For more information about the study, please contact:
Research Specialist Jennifer Fantuzzo, BS
412-692-7949