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The purpose of this study is to model normal and abnormal craniofacial growth and development in patients with and without congenital and acquired disorders of the craniofacial skeleton and to quantify the degree of deformity and to detect possible complications that may follow, such as intracranial hypertension, to allow for better disease stratification, operative planning and timely intervention. The study uses review of medical records and computed tomography (CT) and magnetic resonance imaging (MRI) scans.
Pediatric patients who have been evaluated by the UPMC Children’s Hospital of Pittsburgh Plastic Surgery Division’s Cleft and Craniofacial Center and Neurosurgery Divisions will be eligible to participate, providing that high-quality CT/MRI scans were done and that the patients’ medical conditions align with other inclusion criteria.
Males and Females: All ages
Researchers will compare age-matched scans of patients with congenital and acquired craniofacial anomalies to scans of patients with no structural abnormality, enabling researchers to create a stratification tool for diagnosis and treatment of craniofacial disease.
Visits: None beyond normal treatment for these conditions
Duration: Not applicable
Plastic Surgery Research
Jesse Goldstein, MD
For more information about the study, please contact:
Research Specialist Jennifer Fantuzzo, BS
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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