Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Download our mobile app today - it's free!
The purpose of this multi-center collaborative research study is to help determine the length of time that a person with cystic fibrosis should be given antibiotics intravenously (via IV) for treatment of pulmonary exacerbations. A pulmonary exacerbation is a worsening of respiratory symptoms. Doctors and patients want to make sure the patient gets antibiotics long enough to get better without treating too long and exposing the patient to unnecessary risks.
Subject to certain exclusion criteria, this study is open to participants of both genders, ages 18 and older, who have cystic fibrosis and are going to be put onto IV antibiotics for a pulmonary exacerbation.
Males and females: Ages 18 and older
In this study, participants will be given standard-of-care IV antibiotics. For patients who meet criteria for early robust response within the first week of treatment, IV antibiotics will be provided for a total of either 10 or 14 days, determined by randomization. For patients who do not meet the criteria for early robust response to treatment, IV antibiotics will be provided for a total of either 14 or 21 days, again determined by randomization. Physical exams, tests and blood and sputum samples will be collected at certain intervals.
Duration: 24 to 35 days
Medical University of South Carolina
Cystic Fibrosis Foundation Therapeutics
CF Therapeutics Development Network Coordinating Center
University of Washington
Study Description at National Institutes of Health
Pulmonary Medicine Research
Joseph Pilewski, MD
For more information about the study or enrollment, please contact:
Clinical Research Nurse Coordinator
Rose Lanzo BS, RRT, CRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.