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This observational study aims to learn about the conditions or factors that may lead to Pseudomonas aeruginosa (Pa) infections in children with cystic fibrosis (CF). The information collected will aid in understanding what happens to children with CF with regard to their treatment and health after Pa infection occurs. Children whose cultures become positive for Pa while in the observational study may have the option of taking part in a separate treatment study known as the Early Pseudomonas Infection Control (EPIC) Clinical Trial, while participation in the observational study continues. About 1,700 children with CF will take part in this study in approximately 60 CF clinics across the country. Sixty of them will be from Children’s Hospital of Pittsburgh of UPMC.
Boys and girls with CF up to 12 years of age.
Boys: Up to 12 years
Girls: Up to 12 years
Participation in the study will include recording information from clinic visits, collection of a throat culture, and a yearly blood draw.
Visits: 4 per year
Duration: 2.5 to 5 years
Cystic Fibrosis Foundation Therapeutics, Inc
David M. Orenstein, MD
For information, please contact:
Elizabeth Hartigan, MPH, RH, CCRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
Children’s Hospital of Pittsburgh of UPMC
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.