Publications

Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth
B. Ganapathy, N. Nandhagopal, B. Polizzotti, D. Bennett, A. Asan, Y. Wu, B. Kühn
PLOS ONE
2016 May 13

A cryoinjury model in neonatal mice for cardiac translational and regeneration research
BD Polizzotti, B Ganapathy, BJ Haubner, JM Penninger, B. Kühn
Nature Protocols
2016 Mar

Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window (PDF)
BD Polizzotti, B Ganapathy, S Walsh, S Choudhury, N Ammanamanchi, DG Bennett, CG dos Remedios, BJ Haubner, JM Penninger, B. Kühn
Science Translational Medicine
2015 Apr 1

Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation (PDF)
SE Senyo, RT Lee, B Kühn
Stem Cell Research
2014 Sep

Muscling Up the Heart - A Preadolescent Cardiomyocyte Proliferation Contributes to Heart Growth 
CH Zhang, B Kühn
Circulation Research
2014 Sep 26

New mechanistic and therapeutic targets for pediatric heart failure: report from a national heart, lung, and blood institute working group (PDF)
KM Burns, BJ Byrne, BD Gelb, B Kühn, LA Leinwand, S Mital, GD Pearson, M Rodefeld, JW Rossano, BL Stauffer, MD Taylor, JA Towbin, AN Redington
Circulation
2014 Jul 1

Signalling between microvascular endothelium and cardiomyocytes through neuregulin (PDF)
EM Parodi, B Kühn
Cardiovasc Res
2014 May 1 (Epub 2014 Jan 29)

Moderate and high amounts of tamoxifen in α-MHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death (PDF)
K Bersell, S Choudhury, M Mollova, BD Polizzotti, B Ganapathy, S Walsh, B Wadugu, S Arab, B Kühn
Disease Models & Mech
2013 Nov (posted online 2013 Aug 7)

Cardiomyocyte proliferation contributes to heart growth in young humans (PDF) 
M Mollova, K Bersell, S Walsh, J Savla, LT Das, SY Park, LE Silberstein, CG Dos Remedios, D Graham, S Colan, B Kühn
PNAS
2013 Jan 22

Intrapericardial delivery of gelfoam enables the targeted delivery of periostin peptide after myocardial infarction by inducing fibrin clot formation (PDF) 
BD Polizzotti, S Arab, B Kühn
PLoS ONE
2012 May 10

The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation (PDF) 
B Wadugu, B Kühn B
Am J Physiol Heart Circ Physiol
2012 Mar 16

Taking the load off: Nuclear remodeling after mechanically supporting the failing human heart (PDF) 
C Murry, B Kühn
Circulation
2010 Mar 2

Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury (PDF) 
K Bersell, S Arab, B Haring, B Kühn
Cell
2009 Jul 24


Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair (PDF) 
B Kühn, F Del Monte, RJ Hajjar, YS Chang, D Lebeche, S Arab S, et al.
Nat Med
2007 Aug