COVID-19: The Latest Information from UPMC
Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #8 Nationally by U.S. News & World Report.
Spends Enough Time with You
Recommend This Provider to Family/Friends
Shows Respect to Patients
Explains in a Way You Understand
Transplant SurgeryCritical CarePediatric Transplant Surgery
SurgerySurgical Critical Care
MD, Northwestern University - Feinberg Chicago, IL
Butterworth Hospital Grand Rapids, MI
University of Pittsburgh School of Medicine Pittsburgh, PA University of Pittsburgh School of Medicine Pittsburgh, PA
UPMC PresbyterianUPMC Children's Hospital of Pittsburgh
View Dr. Mazariegos's full list of publications from PubMed.
Listen to Dr. Mazariegos discuss pediatric liver transplantation and his journey to Pittsburgh in the December 2018 episode of "That’s Pediatrics" podcast.
George V. Mazariegos, MD, is the director of Pediatric Transplantation at Children's Hospital of Pittsburgh of UPMC. He also is director of Pediatric Transplantation at the Thomas E. Starzl Transplantation Institute and an associate professor at the University of Pittsburgh in the departments of Surgery, Anesthesiology, and Critical Care Medicine.
Dr. Mazariegos earned a bachelor's degree in medical science at Northwestern University in Evanston, Ill., in 1984. Two years later, he graduated from Northwestern University Medical School. He completed residency training at Michigan State University in Grand Rapids and completed his fellowship training at the University of Pittsburgh in 1993. He joined the Thomas E. Starzl Transplantation Institute in 1994 and Children's Hospital of Pittsburgh in 1997 as co-director of Pediatric Liver and Intestine Transplantation.
Dr. Mazariegos specializes in the treatment of pediatric patients who have liver and/or intestinal disease that require transplantation. He also cares for children who develop acute liver failure and who may require specialized liver support therapies until they recover or until donor organs are available.
Dr. Mazariegos' research focuses on further refining immunosuppression therapy to improve transplant outcomes and quality of life. He currently is leading clinical efforts to evaluate lowering or withdrawing immunosuppression in long-term liver transplant recipients in order to maximize quality of life and minimize post-transplant complications. Dr. Mazariegos also is analyzing immunologic characteristics of patients successfully withdrawn from immunosuppression. This study, sponsored by the Immune Tolerance Network, is attempting to develop a "tolerance assay" that can be used to prospectively characterize patients who may be candidates for less immunosuppression.
Dr. Mazariegos has authored or co-authored more than 70 original articles, more than 80 abstracts and 10 book chapters. He has been active in coordinating the development of bio-artificial liver support systems for use in patients with acute liver failure. He also serves on the Scientific Advisory Board of Studies in Pediatric Liver Transplantation, an international registry of pediatric liver transplantation.
Dr. Mazariegos' work has earned him memberships in numerous professional and scientific societies, including the Society of University Surgeons and the International Pediatric Transplant Association. He was named Critical Care Fellow of the Year in 1992 by the University of Pittsburgh Multidisciplinary Critical Care Training Program, and in 1999 he received Children's Hospital's Service Star Award.
Patient comments are gathered from our Press Ganey Patient Satisfaction Survey and are displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.