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MD, Oregon Health & Science University Portland, OR
University of Pittsburgh School of Medicine Pittsburgh, PA
UPMC Children's Hospital of PittsburghUPMC Magee-Womens Hospital
Dr. Eisses; research focuses on understanding the role of epigenetic modifiers in regulating injury and recovery of the pancreas as it relates to pancreatic disease. His interests reside in the epigenetic regulation of the histone deacetylases (HDACs) in pancreatic recovery after injury, focusing on their action in distinct cell types within the pancreas ; specifically pancreatic stellate cells (PSCs). Injury and inflammation activate PSCs resulting in the remodeling of the pancreatic microenvironment. Dr. Eisses postulates that an alteration in the epigenetic landscape during injury and subsequent recovery is necessary for the altered gene regulation at specific transcriptional sites within distinct pancreatic cell types. Epigenetic changes during PSC activation are required to allow ECM remodeling and to generate the necessary regenerative signals that allow pancreatic exocrine recovery. Prolonged injury or aberrant regulation of PSCs has been implicated in the development or promotion of several pancreatic diseases including chronic pancreatitis and pancreatic cancer. Ongoing studies aim to understand the important regulators of this process with an aim at developing therapeutic interventions.
Mechanisms of pancreatic injury and recovery. Epigenetic mechanisms in Pancreatic recovery following pancreatitis. Role of HDACs in modulating pancreatic recovery following injury.
View Dr. Eisses's full list of publications from PubMed.
Patient comments are gathered from our Press Ganey Patient Satisfaction Survey and are displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
Total Comments: 20
doctor was very understanding
the doctor was very informative and helpful
we love Dr Eisses
Dr Eisses always takes his time with me and asks many questions regarding my overall health, not just my Crohn's. Dr. Eisses is patient and concerned about my health. He offers communication through the CHP app, which I forgot about.
We are happy with the care that was received.
Although we were the last appointment of the day AND had arrived late, Dr. Eisses gave us all of the time we needed to discuss my daughter's health, answer my questions, address my concerns, and ensure we understand the treatment plan.
the doctor is wonderful with my son and truly takes time to listen and care for the patient and our family concerns! Best doctor hands down!!
the last test ordered by the doctor was fine at a hospital closer to where we live. When we hadn't heard back after several days, I called the office and the hospital never sent the results. Dr. Eisses' office was very cordial and returned my call quickly. The results are now uploaded on the myChP site, and I am now awaiting a response to a question I had about what was transcribed. it said it could take about two business days, and we are still within that time frame.
Dr. Eisses listened carefully to me and my daughter and explained thoroughly my daughter's condition and treatment plan.
Dr. Eisses was excellent, he made my son feel comfortable and addressed all are questions so we could understand them.
he is a great listener
Dr Eisses is very insightful and offers nonjudgmental consultation to his patients. He takes his time and answers questions from parents as well as patients. Our wait time was brief, vitals taken quickly and with a smile. Staff was polite and accommodating to our needs for medical excuse for school and payment at the end of the day. I appreciate electronic Rx fills with our mail order provider. Thank you for all you do for our children!
He was very caring and seemed to really care about my daughter's health.
Dr. Eisses was very personable and friendly with my child. He answered all questions and concerns thoroughly.
I am very happy with Dr. Eisses! My son relates well to him, he is understanding and has really gotten to know my son's quirks and how to navigate them.
so glad we made the decision to make my sons's appt with Dr. Eissis! He took so much time with us and thoroughly understood our concerns for our son.
Dr. Eisses is patient and kind. He listened to and discussed my concerns. Dr. Eisses showed me and explained test results to me. Dr. Eisses also offered suggestions for my medicine and offered me the option of seeking an adult GI dr., but I feel comfortable staying in his care for now. So far, our experience has been good.
the provider spent a great amount of time with my son and explained everything in terms that both of us understood. was very respectful to my son.
The doctor was very patient and listened to everything I had to say. He also answered any questions or problems I was concerned about.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.