COVID-19: The Latest Information from UPMC
Children's Hospital is part of the UPMC family.
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #8 Nationally by U.S. News & World Report.
Spends Enough Time with You
Recommend This Provider to Family/Friends
Shows Respect to Patients
Explains in a Way You Understand
Neonatal - Perinatal MedicinePediatrics
MD, Tufts University School of Medicine Boston, MA
Boston Children's Hospital Boston, MA
UPMC Magee-Womens HospitalUPMC HorizonUPMC MercyUPMC AltoonaUPMC Children's Hospital of PittsburghUPMC Williamsport
An attending neonatologist and an assistant professor/early-stage investigator in Pediatrics, Developmental Biology and Immunology at the University of Pittsburgh School of Medicine, Liza Konnikova's focus is on the development of neonatal immunity at mucosal surfaces and its role in the pathogenesis of diverse diseases such as sepsis, preterm labor, necrotizing enterocolitis and very-early onset IBD (VEO-IBD). Her postdoctoral training focused on the development of gastrointestinal (GI) tolerance in children. Through collaborative initiatives, she has shown that a novel subtype of regulatory T-cells exists in the human GI tract and is important in controlling Th17. In Dr. Konnikova's studies of the role of IL10 signaling in mucosal immune development, she has demonstrated that IL10R-deficient patients develop a profound increase in pro-inflammatory cytokines such as IL1b and IL17.
She has pioneered the application of mass cytometry to frozen mucosal biopsies, helping to improve our understanding of mucosal immunity. This innovation has helped to identify novel populations of immune cells in VEO-IBD and to perform serial monitoring of IBD activity in drug trials. In addition to continuing studies on GI immune development in infants and young children, her lab is applying these techniques to gain a better understanding of placental immune development and postulates that there are potential infection-independent immune triggers in the placenta that induce preterm labor and set up a pro-inflammatory cascade in the infants.
Visit Dr. Konnikova's lab website.
View Dr. Konnikova's full list of publications from PubMed.
Patient comments are gathered from our Press Ganey Patient Satisfaction Survey and are displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.