COVID-19: Vaccines, Testing, and Treatment Read the Latest
Children's Hospital is part of the UPMC family.
Our Sites
Be safe anytime, anywhere.
To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
A resource for our network of referring physicians.
For more information about research, please call our main office at 412-692-6438.
Ranked #9 Nationally by U.S. News & World Report.
The Kasai procedure is named after Dr. Morio Kasai, the Japanese surgeon who developed it in 1951. You might also hear your health care provider refer to it as a "Roux-en-Y" or a "hepatoportojejunostomy" (pronounced "he-pat-o-port-o-jeh-joo-nah-sto-me").
The liver has ducts, so that the bile it produces can drain into the intestine and help with digestion of food. If these ducts are blocked, the Kasai procedure is a way to surgically bypass them and prevent liver damage. It is often the preferred treatment for biliary atresia.
To perform the Kasai procedure, surgeons first carefully remove the damaged ducts outside of the liver. They use a small segment of the patient's own intestine to replace the ducts at the spot where bile is expected to drain. This segment not only connects to the liver, but also connects to the rest of the intestine. The Y-shaped passageway formed by the Kasai operation allows bile to flow from the liver into the intestine.
If your child needs a Kasai procedure, he or she will usually spend seven to ten days recovering in the hospital. During this time, the Kasai will heal, and doctors will give your child medications to prevent ascites, or excessive fluid build-up.
In the long-term, antibiotic therapy helps reduce the risk of infection entering the liver through the intestine. Although Kasai procedure is not a permanent cure for biliary atresia, in many cases it allows patients to grow and remain in good health for several years. This delays (or in about 25% of children, eliminates) the need for a liver transplant.
When the Kasai procedure is done at an early age (younger than three months), about 80 percent of patients have some bile flow. In nearly 30 percent of those infants, enough bile is able to drain from the liver that bilirubin levels return to normal. In the smaller number of patients who don't benefit from the operation, some of the obstructed bile ducts are inside the liver as well as outside. When this happens, liver transplantation is needed sooner to correct the problem.
Learn more about other Liver Transplant Procedures.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.