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412-692-6740 Phone
412-692-6752 Fax

Sophie Chen, PhD

Sophie Xiaohua Chen, PhD
4401 Penn Avenue, Suite Floor 9
Pittsburgh, PA 15224
412-692-6740 Phone
412-692-6752 Fax

Education and Training

Medical School:

1995 PhD, John Curtin School of Medical Research, Australian National University, Australia 


2002 Postdoctoral fellow, Hematology/Oncology, St Jude Children’s Research Hospital, Memphis, Tenn.

Academic Appointments:

2011 Scientist, Division of Bone Marrow Transplantation and Cellular Therapy, The Children’s Hospital of Philadelphia, Philadelphia, Pa.
2007 Research Associate/Scientific Manager, Division of Stem Cell Transplantation, St Jude Children’s Research Hospital, Memphis, Tenn.


  • American Society of Hematology
  • International Society of Cellular Therapy
  • Association of Clinical Research Professional
  • Collaborative Institutional Training Initiative


  • Chen, X et al "A strategy for signle nucleotide polymorphism analysis of chimerism for somatic cell therapy". Cytotherapy 2010;12(8):;35(5)1035-43.
  • Chen, X et al "Molecular monitoring of immune reconstitution after haploidentical stem cell transplantation" Curr Stem Cell Res Ther  2008;3(2):75-78.
  • Chen, X et al "A novel approach for the analysis of T-cell reconstitution by using a T-cell receptor beta-based oligonucleotide microarray in hematopoietic stem cell transplantation". Exp Hematol.  2007:35(5):831-41.

Research Interests

  • Cellular and molecular monitoring immune regeneration, immune deficiency, and immune tolerance during hematopoietic stem cell transplantation
  • Mechanism and character of immune tolerance in hematopoietic stem cell transplantation

Active Research Projects / Grants

  • Regulatory T cells and tolerance after Blood and Marrow Transplantation
Last Update
December 16, 2014
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Last Update
December 16, 2014