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Children's Hospital of Pittsburgh of UPMC is a leader in the use and implantation of vagus nerve stimulation to treat pediatric epilepsy, performing 60 vagus nerve stimulator (VNS) implantations in 2009, more than any other pediatric hospital in the United States. Children's has ranked in the top two pediatric hospitals in the United States in the implantatation of VNS devices since 2005.
A Vagus Nerve Stimulator (VNS) is a device used to treat seizures when seizure drugs are not effective and surgery is not possible. VNS consists of a pacemaker-like generator that is implanted in the chest wall and is programmed by the physician to stimulate the vagus nerve in the neck. Thin wires are threaded under the skin and woven around the vagus nerve in the neck. This device often reduces the frequency of seizures and can also be activated by a patient or caregiver to stop seizures just as they are beginning.
Vagus nerve stimulation can work for any seizure type, but it is most often used for children with debilitating epilepsy. The VNS device often becomes more effective the longer it is in, and physicians typically know within six months if the VNS is helping to control the child's seizures.
Children are given a general anesthesia prior to the surgery. Sometimes only a local anesthetic is used.
Two small incisions are required: one on the left lower side of the neck and a second along the left side of the chest. The VNS device, which is about the size of a silver dollar, is implanted into the chest wall.
The vagus nerve is located between the carotid artery and the jugular vein. Three small platinum electrodes are wrapped around the nerve and the wire is tunneled beneath the skin toward the left side of the chest. The electrode leads are attached to the generator, and the generator and leads are tested prior to closing the skin incisions.
The generator may be turned on the day following the surgery or at the first post-surgical visit. Your child will be reassessed in seven to 10 days for a wound check, and the generator may be turned on or adjusted. Parents will be shown how to use a magnet to control a seizure. Waving the magnet over the generator may stop or shorten a seizure.
Children who are implanted with a VNS usually return home the same day following their surgery. Sometimes a hospital stay of one night is necessary.
Side effects of VNS therapy include hoarseness and discomfort in the neck when the generator is on. This indicates that the VNS is functioning. The incidence of children experiencing serious complications or unanticipated outcomes has been rare and outcomes have been excellent.
To make a referral, schedule an appointment, or request an evaluation for a child or teen, call at 412-692-6928.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
Children’s Hospital of Pittsburgh of UPMC
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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