Research

Eustachian Tube Development Study

Eustachian Tube Growth and Development: Anatomy/Function

Protocol Description

This study measures Eustachian tube function and facial growth over time in three groups of children: one with recurrent ear infections, one with chronic middle ear fluid, and one with little past history of otitis media. These measures will be used to determine if facial growth is related to improved Eustachian tube function and to the resolution of otitis media. Additionally, findings will be used to see if better Eustachian tube function explains why young children “outgrow” otitis media as they get older, and to determine if these measures are different for the children in the three groups.

Eligibility Criteria

Children are entered into the study at age 3, assigned by their history of disease to one of the groups, and followed until age 7.
Boys: 3 years old
Girls: 3 years old

Requirements
Children enrolled in the study will have examinations done approximately every 6 months until they are 7 years old. During examinations a variety of tests will be performed to measure Eustachian tube function. Facial measurements will be recorded and dental examinations will be done. At specific intervals, other specialized tests, such as cephalometric x-rays and magnetic resonance imaging, will be done on some children.
Visits: 9 to 10
Duration: About 4 years (through age 7)

Status: Open for Enrollment

Source of Support
National Institute on Deafness and Other Communication Disorders

Additional Resources
Study description at the National Institutes of Health