Research

Neonatal Neurocognitive Assessment

Correlation of Neonatal Brain Imaging and Neurocognitive Assessment

Protocol Description

The purpose of this multi-site study is to determine if certain types of tests and exams can help with early screening, diagnosis and treatment of brain injury in newborns as well as identify a connection between MR imaging (magnetic resonance imaging and magnetic resonance spectroscopy) and neuro-developmental outcome. Through this protocol, researchers will collect and compare information from cranial ultrasounds, MR imaging scans, neurological exams and neuropsychological assessments of children.
 

Eligibility Criteria

The study is open to newborn infants of both genders, who were born premature, have congenital heart disease or were born full-term and healthy.
Males: Newborns
Females: Newborns
 
Requirements
With parental permission, researchers will conduct MR brain imaging and/or cranial ultrasound of participating newborns. Alternately, researchers will collect existing information in cases where clinical brain imaging or cranial ultrasound scans were already performed as part of a child’s standard care. When participants are about 18 months of age, a neuropsychologist will conduct developmental tests. At age 3, and again at age 6, participants will receive a short neurological exam followed by a visit with a neuropsychologist. Also at age 6, additional MR imaging will be performed.
Visits: 5
Duration: 6 years
 
Status: Open for Enrollment
 
Source(s) of Support
National Institute of Neurological Disorders and Stroke
National Institutes of Health
 

Primary Investigator(s)

Ashok Panigrahy, MD

Contact Information

For information or to enroll, please contact:
Fern Wasco
412-692-7396

Last Update
March 13, 2014
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Last Update
March 13, 2014
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