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Thank you to Stephanie McMahon, WWE chief brand officer and Children's Hospital of Pittsburgh Foundation board member, and Paul Levesque, WWE executive vice president, for the initial gift allowing UPMC Children's to establish this treatment suite.
There's new hope for children with neuroblastoma — an aggressive form of childhood cancer.
Infants tend to have a less aggressive form of the disease. Although rarer, neuroblastoma can also occur in teens and young adults.
MIBG is a compound that easily absorbs into neuroblastoma cells, often used for tumors that have returned. At the MIBG Therapy Suite at UPMC Children's Hospital of Pittsburgh, we're using it as a front-line treatment to kill cancer cells.
To learn more about MIBG treatment at UPMC Children's Hospital of Pittsburgh, call 412-692-8570.
Doctors have used MIBG since the late 1980s to scan for tumors. But we've recently found that increased doses can start to kill tumors instead of just find them.
When combined with radioactive iodine, MIBG can travel directly to the tumor and kill the cancer cells without harming healthy tissue.
That's good news for parents of children with cancer. Doctors diagnose about 700 new cases of neuroblastoma each year in the United States — mostly affecting children under 5.
Common front-line treatments for neuroblastoma include:
Not all hospitals have MIBG rooms. UPMC Children's Hospital has the only one in western Pa.
Adding the MIBG Therapy Suite for childhood cancer treatment lets us take part in a long-term study of MIBG treatment. The Children's Oncology Group leads the study.
MIBG therapy is a standard treatment for people who have relapsed. The goal of this study is to gauge MIBG's effectiveness as the first form of treatment.
The day before MIBG treatment begins, your child will come to the hospital to receive:
MIBG therapy requires strict safety measures. Your child's treatment will take place in a lead-lined room with a 1,400-pound door.
During treatment, we will mildly sedate your child and dispense the MIBG through the IV. Your child will get his or her nutrients from a feeding tube through the nose.
After treatment, your child must stay in the lead-lined room alone for 5 to 7 days because of the radioactivity. As the radiation levels decrease, you can spend more time with your child.
Since your child must stay in bed, we make the surroundings as warm as possible. There's a big-screen TV to watch, and you can stay in the room right next door. It has a window, so you and your child can see each other.
In case a child needs critical care, the MIBG Therapy Suite is also set up like an ICU with:
Before we can admit a child to the MIBG Therapy Suite at UPMC Children's, parents must:
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With MyCHP, you can request appointments, review test results, and more.
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To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.