Pediatric Heart Disease Research

The Cardiovascular Research Lab at Children’s Hospital of Pittsburgh of UPMC is world-renowned for its heart disease research.

We're always working to understand the causes of congenital heart disease and find new ways to treat children with all types of heart problems.

See our studies below or learn more about heart disease research at Children's Hospital of Pittsburgh.


Adult Congenital Heart Disease Clinical Care Evaluation

Utilization and Perception of Care by Physician Extenders in the Adult Congenital Heart Disease Program

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Aortic Coarctation Treatment with Covered CP Stent™ – COAST II

Covered Cheatham Platinum CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated with Coarctation of the Aorta (COAST II) – Continued Study Access

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Aortic Coarctation Treatment with CP Stent™ – COAST

Coarctation of the Aorta Stent Trial (COAST) – Continued Study Access

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Beta Blocker Therapy for Marfan Syndrome

Trial of Beta Blocker Therapy vs Angiotensin II Receptor Blocker Therapy in Individuals with Marfan Syndrome

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Comparing Treatments for Coarctation of the Aorta

Comparison between Surgical vs. Balloon Angioplasty vs. Intravascular Stent Placement for Recurrent or Native Coarctation of the Aorta

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Coping with Heart Disease – A Study of Adolescents and Adults

Coping Mechanisms, Gender Difference, and Cardiovascular Risk in Adolescents and Adults with Congenital Heart Disease

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Dexmedetomidine for Sedation in Medical Procedures – Phase IV

Dexmedetomidine in Pediatric Subjects Undergoing Procedure-Type Sedation

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Fontan Procedure Physiology

Do Serum Biochemical and Hematopoietic, or Stool Biomarkers Predict Low Cardiac Index in Patients with Fontan Physiology?

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Pediatric Heart Transplant - Alloantibodies Impact Study

Alloantibodies in Pediatric Heart Transplantation

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Pediatric Heart Transplant - Fibrosis Quantification Study

MRI Quantification of Cardiac Fibrosis after Heart Transplantation

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Sexual Dysfunction and Congenital Heart Disease – Pilot Study

Female Sexual Dysfunction Among Adults with Complex Congenital Heart Disease

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SVT Treatment with Dexmedetomidine

Dexmedetomidine vs. Adenosine: Electrophysiologic Effects and Therapeutic Use for Terminating Supraventricular Tachycardia

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Treating Atrial Septal Defects with Amplatzer

Closure of Atrial Septal Defects with the Amplatzer® Septal Occluder Post Market Study

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Transplant EBV Disease Study

Transplant Epstein-Barr Virus (EBV) Disease – Pathogenesis and Immunotherapy

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