Blood and Marrow Transplantation and Cellular Therapies Clinical Studies

The Division of Blood and Marrow Transplantation and Cellular Therapies at Children’s Hospital of Pittsburgh of UPMC maintains an active research program that includes clinical studies in pursuit of new and novel therapies to treat patients with high-risk leukemia or lymphoma, and for those afflicted with other life-threatening inherited conditions that can lead to autoimmune diseases. Select a study below to review a brief description and requirements. Parents or guardians of children who might be eligible are encouraged to inquire about enrollment. Contact information is listed at the end of each study.

Thank you for exploring these opportunities and helping us to find cures and prevent childhood disease.

Clinical Studies


Crohn's Disease Treatment using Blood Stem Cells – Phase I/II

Autologous Stem Cell Transplantation with CD34 Selected Peripheral Blood Stem Cells (PBSC) in Pediatric and Young Adult Patients with Severe Crohn's Disease Read more

Immunodeficiency and End-Stage Lung Disease Treatment

Bilateral Orthotopic Lung Transplant in Tandem With CD3+ and CD19+ Cell Depleted Bone Marrow Transplant From Partially HLA-Matched Cadaveric Donors Read more

National Marrow Donor Program

National Marrow Donor Program Recipient Research Database and Research Sample Repository for Patients Undergoing Unrelated Marrow Transplants Read more

Non-Malignant Marrow Disorder Treatment using Reduced Intensity Conditioning – Phase II

Study of Reduced-Intensity Conditioning In Patients With Non-Malignant Disorders Undergoing Umbilical Cord, Bone Marrow, or Peripheral Blood Stem Cell Transplantation Read more

Paul Szabolcs, MD

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Craig Byersdorfer, MD., PhD.

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Rakesh Goyal, MD

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Randy Windreich, MD

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Mark Vander Lugt, MD

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