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The purpose of this multi-center study is to evaluate the effects of treatment of influenza (flu) with zanamivir delivered intravenously rather than via traditional inhaler. Specifically, researchers will be monitoring the safety and tolerability of the medicine.
Subject to certain exclusion criteria, this study is open to individuals of both genders ages six months through adult who are hospitalized with the flu.
Males: Ages 6 months through adult
Females: Ages 6 months through adult
Participants will be given intravenous dosages of zanamivir twice a day for 5 days and if needed, as determined by the patient’s doctor, for up to 10 days. Blood sampling will be done throughout the period in which the medicine is administered and electrocardiograms will be done at certain intervals. Patients will be recalled to the hospital for final tests following the study.
Visits: Requires hospitalization initially, then telephone follow-up and a visit after discharge
Duration: 4 to 5 weeks, inclusive of follow-up
Study description at National Institutes of Health
Marian G. Michaels, MD, MPH
For information, or to enroll, please contact:
Diane Gwin RN, BSN, MSN, CCRC
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.