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This pilot study is being done to assess whether saliva can be utilized instead of blood to monitor anti-seizure medication levels in babies being treated for seizures. Such medications usually require regular blood monitoring to make sure the medication is at an appropriate level. If saliva could be reliably used instead of blood, medication monitoring could be done painlessly, avoiding multiple blood draws.
Babies who are already at Children’s Hospital of Pittsburgh of UPMC or Magee Women’s Hospital and who experience seizures that require treatment with Phenobarbital will be considered for inclusion in this study.
Boys: Newborns up to 30 days
Girls: Newborns up to 30 days
In addition to blood draws that are taken as part of standard medical care within 24 to 48 hours of the administration of Phenobarbital, a saliva sample will also be obtained.
Visits: Occurs during hospitalization
Duration: Depends on length of hospital stay
Monica Naik, MD
To get started, please contact:
Monica Naik, MD
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.