Spotlight on Research

Take a look at some of the exciting research developments at UPMC Children’s Hospital of Pittsburgh. As we advance the frontiers of pediatric research, we’ll spotlight the progress of our most promising projects.

Gene Therapy Reverses Autoimmune Diabetes in Mice

Reversing autoimmune type 1 diabetes without immunosuppression has proven to be extremely difficult, but in a study published in Cell Stem Cell, (Jan. 4, 2018) researchers at UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine report achieving that outcome in mice using gene therapy.

New Technique for Maintaining Cancer Stem Cells May Be Key to Cure

A new technique for maintaining cancer stem cells in the lab may prove to be the key to stopping them in the body, according to scientists at the John G. Rangos Sr. Research Center at Children’s Hospital of Pittsburgh of UPMC.

Anti-Seizure Drug May Also Cure Liver Disease 

A new research discovery has found that a drug trusted to treat seizures may also eliminate the most common genetic cause behind pediatric liver transplants…and potentially even more diseases.

Giving Injured Hearts a Lift

Research has demonstrated that stem cells taken from one's own arm or leg muscles may help in the repair of heart damage - just one of many promising stem therapies being explored by Children's Stem Cell Research Center.

Ear Tubes Often Unnecessary

A long-running study shows that fluid in the middle ear does not impair development and ear tubes may not always be necessary.

Female Stem Cells Are Sturdier

Scientists find stem cells from females regenerate skeletal muscle more efficiently.