Severe Asthma Investigation

Severe Asthma Research Program: Inflammation, Myofibroblasts and Loss of Elastic Recoil in Severe Asthma

Protocol Description

This multi-center study uses extensive testing to develop a more complete understanding and characterization of asthma and to determine why some asthmatics do not respond to current asthma medications.

Eligibility Criteria

Boys and girls, ages 6 to 17, with mild to moderate and severe asthma are eligible to participate.
Boys: Ages 6 to 17
Girls: Ages 6 to 17


Through a series of 3 visits, asthmatic children will be tested at the Pediatric Clinical Translational Research Center and the Pulmonary Function Laboratory of Children’s Hospital of Pittsburgh of UPMC. Tests will include questionnaires about the child’s health, allergy tests, breathing tests, urine collection and blood draws in the first “qualifying” visit. Subsequent visits will involve more extensive pulmonary function testing.
Visits: 3
Duration: 1 month

Status: Open for Enrollment

Source(s) of Support

National Institutes of Health

Primary Investigator

Shean Aujla, MD

Contact Information

For more information about the study or enrollment, please contact:
Tracey Dill, RTT