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To find a pediatrician or pediatric specialist, please call 412-692-7337 or search our directory.
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For more information about research, please call our main office at 412-692-6438.
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The placenta is unlike any other human organ. Given its essential role in protecting the fetus, the placenta must function as a barrier and conduit between the maternal and fetal environments and serve as an active immunological tissue that responds to microbes present in the maternal circulation. Our research program asks two central questions:
Our studies have established a new and important paradigm – that in addition to its role as a physical barrier, the placenta is a dynamic and highly reactive chemical barrier that uses multiple classes of molecules, including type III interferons and microRNAs, to protect the fetus and maternal host from viral infections. However, our investigations continue to probe important questions to learn if there are differences in the mechanisms employed by the placenta to restrict microbial access at different stages of gestation and to understand what mechanisms are used by the placenta to defend against non-viral pathogens. Further, we hope to define the influence of the systemic maternal immune response on placental antimicrobial defenses.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh
One Children’s Hospital Way
4401 Penn Ave.
Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
With myCHP, you can request appointments, review test results, and more.
For questions about a hospital bill call:
To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Visit Children's Hospital of Pittsburgh Foundation's website to make a donation online.